TB-Profiler result

Run: ERR4815803
Summary

Run ID: ERR4815803

Sample name:

Date: 01-04-2023 14:04:25

Number of reads: 1014295

Percentage reads mapped: 98.88

Strain: lineage4.8

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 764567 p.Lys400Glu missense_variant 0.18
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 0.98
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474239 n.582G>T non_coding_transcript_exon_variant 0.17
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.33
rrl 1475104 n.1447T>C non_coding_transcript_exon_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154044 p.Thr690Pro missense_variant 0.12
katG 2155789 p.His108Pro missense_variant 0.22
PPE35 2170066 p.Ala183Thr missense_variant 0.5
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746968 p.Gly211Arg missense_variant 0.14
fbiD 3339363 p.Asp82Glu missense_variant 0.2
Rv3083 3448387 c.-117C>A upstream_gene_variant 0.12
Rv3236c 3612251 c.865delT frameshift_variant 0.15
fbiA 3640904 p.Ala121Val missense_variant 1.0
rpoA 3878535 c.-28G>T upstream_gene_variant 0.4
embC 4241605 c.1744delA frameshift_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244083 p.Ala284Asp missense_variant 0.18
embB 4249647 p.Arg1045Leu missense_variant 0.17
aftB 4267501 p.Pro446Ser missense_variant 0.17
ethA 4328034 c.-561C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0