TB-Profiler result

Run: ERR4816089
Summary

Run ID: ERR4816089

Sample name:

Date: 01-04-2023 14:14:07

Number of reads: 3792419

Percentage reads mapped: 95.76

Strain: lineage4.2.2.2

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 0.99
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.81 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.13
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.14
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.33
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.29
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.29
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.31
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.44
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.43
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.41
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.67
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.67
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.6
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.12
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.59
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.59
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.68
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.71
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.78
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.8
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.77
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.68
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.89
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.8
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.82
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.76
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.42
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.33
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.36
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.36
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.4
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.4
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.4
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.44
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.5
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.5
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.56
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.83
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.84
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.82
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.82
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.86
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.15
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.78
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.76
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.89
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.6
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.8
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.17
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.17
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.43
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.36
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.36
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.33
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.31
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.38
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.31
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.17
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.17
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.25
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.26
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.25
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.25
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.11
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.18
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.18
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.29
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.19
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.29
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.18
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.15
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.15
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 1.0
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.4
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.4
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 0.4
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.5
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.8
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.8
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.67
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.67
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.67
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 1.0
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.25
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.29
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.29
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.22
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.22
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.22
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.22
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.2
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.2
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.4
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.15
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.14
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.38
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.12
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.12
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.46
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.4
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.28
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.26
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.15
inhA 1674450 c.249G>A synonymous_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.99
embA 4242643 c.-590C>T upstream_gene_variant 0.99
whiB6 4338453 c.69A>C synonymous_variant 1.0
whiB6 4338709 c.-188G>C upstream_gene_variant 1.0
whiB6 4338451 c.-189_70del frameshift_variant&start_lost 1.0