TB-Profiler result

Run: ERR4816238
Summary

Run ID: ERR4816238

Sample name:

Date: 01-04-2023 14:19:08

Number of reads: 2112897

Percentage reads mapped: 88.89

Strain: lineage4.1.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.99
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 766070 c.2701C>T synonymous_variant 0.98
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 0.14
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.14
rrs 1472349 n.504A>T non_coding_transcript_exon_variant 0.15
rrs 1472374 n.529T>A non_coding_transcript_exon_variant 0.21
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.23
rrs 1472382 n.537G>T non_coding_transcript_exon_variant 0.23
rrs 1472390 n.545T>C non_coding_transcript_exon_variant 0.23
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 0.23
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.14
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.13
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.12
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 0.33
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 0.33
rrl 1475540 n.1883C>T non_coding_transcript_exon_variant 0.25
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 0.33
rrl 1475550 n.1893A>G non_coding_transcript_exon_variant 0.33
rrl 1475553 n.1896G>C non_coding_transcript_exon_variant 0.33
rrl 1475555 n.1898T>G non_coding_transcript_exon_variant 0.33
rrl 1475571 n.1914A>T non_coding_transcript_exon_variant 0.29
rrl 1475575 n.1918C>A non_coding_transcript_exon_variant 0.29
rrl 1475577 n.1920C>G non_coding_transcript_exon_variant 0.29
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.36
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.35
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.35
rrl 1476384 n.2727G>A non_coding_transcript_exon_variant 0.35
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.38
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.38
rrl 1476532 n.2875T>C non_coding_transcript_exon_variant 0.18
rrl 1476543 n.2886G>C non_coding_transcript_exon_variant 0.25
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3641447 p.Thr302Met missense_variant 1.0
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
ethR 4327021 c.-528G>A upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0