TB-Profiler result

Run: ERR4816293
Summary

Run ID: ERR4816293

Sample name:

Date: 01-04-2023 14:21:09

Number of reads: 1868951

Percentage reads mapped: 99.13

Strain: lineage4.1.2.1

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.2 Euro-American T;H None 1.0
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.17 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.2
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.2
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.4
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.2
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.18
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.18
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.14
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.14
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.15
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.15
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.17
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.18
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.18
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.36
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.12
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.31
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.25
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.11
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.26
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.3
rrs 1472689 n.844C>T non_coding_transcript_exon_variant 0.16
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.23
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.12
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.11
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.3
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.2
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.19
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.16
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.16
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.1
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.21
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.1
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.1
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.18
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.19
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.19
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.25
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.13
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.13
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.11
rrl 1474439 n.783_784insGTT non_coding_transcript_exon_variant 0.5
rrl 1474447 n.790G>A non_coding_transcript_exon_variant 0.75
rrl 1474451 n.794T>C non_coding_transcript_exon_variant 0.6
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.75
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.6
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.5
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.5
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.5
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.5
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.5
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.5
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.5
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.5
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.5
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.5
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.5
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.33
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.45
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.62
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.62
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.33
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.25
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.5
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.43
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.14
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.22
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.13
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.13
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.12
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.1
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.15
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.18
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.11
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0