TB-Profiler result

Run: ERR4816746
Summary

Run ID: ERR4816746

Sample name:

Date: 01-04-2023 14:36:29

Number of reads: 2964317

Percentage reads mapped: 98.08

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576263 c.916C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.13
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.13
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.1
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.21
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.12
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.17
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.17
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.13
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.12
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.12
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.2
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.12
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.12
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.11
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.1
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.13
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.19
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.26
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.14
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.13
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.15
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.17
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.17
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.15
rrl 1474581 n.924C>T non_coding_transcript_exon_variant 0.18
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.17
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.18
rrl 1474826 n.1169T>C non_coding_transcript_exon_variant 0.2
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.2
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.18
rrl 1474852 n.1195T>C non_coding_transcript_exon_variant 0.2
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.18
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3064875 c.1317C>G synonymous_variant 1.0
ald 3086987 p.Gln56His missense_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fprA 3474119 p.Met38Thr missense_variant 1.0
fprA 3474925 p.Thr307Ala missense_variant 1.0
fbiA 3641477 p.Asp312Gly missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338596 c.-75G>A upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0