TB-Profiler result

Run: ERR4817455
Summary

Run ID: ERR4817455

Sample name:

Date: 01-04-2023 15:00:04

Number of reads: 826684

Percentage reads mapped: 99.53

Strain: lineage4.2.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7935 p.Glu212Lys missense_variant 0.15
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490988 p.Leu69Pro missense_variant 0.12
fgd1 491523 c.745delT frameshift_variant 0.11
mshA 576077 c.730C>T synonymous_variant 1.0
rpoB 761489 c.1683G>A synonymous_variant 1.0
rpoC 764539 c.1170C>A synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 779465 p.Gln159Arg missense_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304422 p.Ala498Thr missense_variant 0.11
embR 1416806 p.Glu181Gly missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1834734 p.Ala398Val missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918164 c.225G>A synonymous_variant 1.0
katG 2155914 c.198G>A synonymous_variant 0.14
PPE35 2167766 c.2847C>G synonymous_variant 0.15
PPE35 2169738 p.Thr292Ile missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289657 c.-416G>T upstream_gene_variant 0.15
kasA 2518227 p.Ala38Asp missense_variant 0.15
ahpC 2726571 p.Ala127Thr missense_variant 0.12
folC 2747186 p.Ser138Leu missense_variant 0.14
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
thyA 3073754 p.Glu240Gln missense_variant 0.11
thyA 3073877 p.Phe199Leu missense_variant 0.17
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3640352 c.-191G>A upstream_gene_variant 0.12
clpC1 4039797 p.Asp303Gly missense_variant 0.14
panD 4044039 c.243G>T synonymous_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243461 p.Ser77Pro missense_variant 1.0
embB 4249474 c.2961C>T synonymous_variant 0.11
aftB 4269060 c.-224G>T upstream_gene_variant 0.12
ethA 4326454 c.1020C>T synonymous_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0