Run ID: ERR4817767
Sample name:
Date: 01-04-2023 15:11:08
Number of reads: 5683680
Percentage reads mapped: 94.27
Strain: lineage4.6.2.2
Drug-resistance: HR-TB
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.6 | Euro-American | T;LAM | None | 1.0 |
lineage4.6.2 | Euro-American | T;LAM | RD726 | 1.0 |
lineage4.6.2.2 | Euro-American (Cameroon) | LAM10-CAM | RD726 | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|---|---|---|---|---|
rrs | 1472733 | n.888G>A | non_coding_transcript_exon_variant | 0.38 | streptomycin |
katG | 2155167 | p.Ser315Thr | missense_variant | 1.0 | isoniazid |
embB | 4249583 | p.Asp1024Asn | missense_variant | 1.0 | ethambutol |
gid | 4408100 | c.102delG | frameshift_variant | 1.0 | streptomycin |
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 |
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
mmpR5 | 778298 | c.-692C>T | upstream_gene_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrs | 1472714 | n.869A>G | non_coding_transcript_exon_variant | 0.25 |
rrs | 1472716 | n.871C>T | non_coding_transcript_exon_variant | 0.22 |
rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.35 |
rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.35 |
rrs | 1472767 | n.922G>A | non_coding_transcript_exon_variant | 0.24 |
rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.38 |
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.12 |
rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.4 |
rrs | 1472803 | n.958T>A | non_coding_transcript_exon_variant | 0.4 |
rrs | 1473276 | n.1431A>G | non_coding_transcript_exon_variant | 0.17 |
rrs | 1473290 | n.1445C>T | non_coding_transcript_exon_variant | 0.14 |
rrs | 1473291 | n.1446G>A | non_coding_transcript_exon_variant | 0.14 |
rrs | 1473301 | n.1456T>C | non_coding_transcript_exon_variant | 0.12 |
rrl | 1475876 | n.2219A>T | non_coding_transcript_exon_variant | 0.5 |
rrl | 1476229 | n.2572C>T | non_coding_transcript_exon_variant | 0.33 |
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.2 |
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.2 |
rrl | 1476268 | n.2611A>T | non_coding_transcript_exon_variant | 0.18 |
rrl | 1476275 | n.2618T>A | non_coding_transcript_exon_variant | 0.18 |
rrl | 1476279 | n.2622G>A | non_coding_transcript_exon_variant | 0.17 |
rrl | 1476280 | n.2623A>C | non_coding_transcript_exon_variant | 0.17 |
rrl | 1476337 | n.2680C>A | non_coding_transcript_exon_variant | 0.18 |
inhA | 1673393 | c.-809G>C | upstream_gene_variant | 1.0 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
Rv1979c | 2221746 | c.1416_1418dupCCG | disruptive_inframe_insertion | 0.97 |
Rv1979c | 2222657 | p.Lys170Glu | missense_variant | 1.0 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
Rv3083 | 3448567 | p.His22Asp | missense_variant | 1.0 |
fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 |
ddn | 3987011 | c.168C>T | synonymous_variant | 1.0 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
aftB | 4267272 | p.Lys522Arg | missense_variant | 1.0 |
ethR | 4326739 | c.-810G>C | upstream_gene_variant | 1.0 |
ethA | 4326863 | p.Met204Thr | missense_variant | 1.0 |
ethA | 4328004 | c.-531C>T | upstream_gene_variant | 0.99 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |