TB-Profiler result

Run: ERR4818309
Summary

Run ID: ERR4818309

Sample name:

Date: 01-04-2023 15:29:14

Number of reads: 1221031

Percentage reads mapped: 99.86

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6877 c.-425G>T upstream_gene_variant 0.1
mshA 576723 p.Val459Ala missense_variant 0.22
ccsA 620748 c.858T>G synonymous_variant 0.25
rpoB 761152 p.Leu449Gln missense_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473125 n.1280A>C non_coding_transcript_exon_variant 0.1
rrl 1473710 n.55delG non_coding_transcript_exon_variant 0.13
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.25
rrl 1475316 n.1659G>T non_coding_transcript_exon_variant 0.67
rrl 1475392 n.1735C>T non_coding_transcript_exon_variant 0.33
rrl 1476104 n.2447T>C non_coding_transcript_exon_variant 0.17
PPE35 2167965 p.Ala883Gly missense_variant 0.1
PPE35 2167967 c.2646A>C synonymous_variant 0.1
PPE35 2170048 p.Leu189Val missense_variant 0.17