TB-Profiler result

Run: ERR4819319
Summary

Run ID: ERR4819319

Sample name:

Date: 01-04-2023 16:02:39

Number of reads: 644891

Percentage reads mapped: 99.44

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8489 p.Lys396Asn missense_variant 1.0
gyrA 8709 p.Ala470Thr missense_variant 0.11
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575714 p.Tyr123His missense_variant 0.12
mshA 575747 p.Ala134Ser missense_variant 0.12
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1305082 c.2153delA frameshift_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170363 p.Glu84Gln missense_variant 0.18
PPE35 2170400 c.213G>C synonymous_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518816 c.702C>T synonymous_variant 0.12
kasA 2518879 c.765A>G synonymous_variant 0.11
kasA 2518882 c.768C>A synonymous_variant 0.11
eis 2714890 p.Arg148His missense_variant 0.18
ahpC 2726210 c.18T>C synonymous_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.45
ahpC 2726341 p.Val50Gly missense_variant 0.37
Rv2752c 3066095 p.Val33Ile missense_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474143 p.Trp46Tyr missense_variant 0.11
fbiA 3641447 p.Thr302Met missense_variant 1.0
alr 3840429 p.Asn331Ser missense_variant 0.11
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4245503 c.2271G>A synonymous_variant 0.18
embB 4247918 p.Arg469Ser missense_variant 0.13
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0