TB-Profiler result

Run: ERR4819400
Summary

Run ID: ERR4819400

Sample name:

Date: 01-04-2023 16:05:14

Number of reads: 584466

Percentage reads mapped: 98.34

Strain: lineage4.3.2

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 759952 p.Asp49Gly missense_variant 0.14
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 765964 p.Leu865Phe missense_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776085 p.Val799Ala missense_variant 0.17
mmpL5 778061 p.Gln140His missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304689 c.1762delG frameshift_variant 0.12
embR 1416864 c.483dupC frameshift_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673193 c.-247T>C upstream_gene_variant 0.12
rpsA 1834035 p.Ile165Asn missense_variant 0.25
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154226 p.Gly629Asp missense_variant 0.18
katG 2154816 c.1296C>A synonymous_variant 0.18
PPE35 2168774 c.1838delC frameshift_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073849 c.622delA frameshift_variant 0.22
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086915 c.96G>A synonymous_variant 0.29
ald 3086922 p.Ile35Val missense_variant 0.25
Rv3083 3449854 p.Met451Val missense_variant 0.1
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568471 p.Ile70Thr missense_variant 0.18
Rv3236c 3613275 c.-159C>T upstream_gene_variant 0.14
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4039714 p.Tyr331His missense_variant 0.22
clpC1 4040540 c.164delC frameshift_variant 0.22
panD 4044179 p.Ala35Ser missense_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246286 c.-228G>A upstream_gene_variant 0.14
aftB 4268781 p.Trp19Leu missense_variant 0.29
whiB6 4338248 p.Leu92Met missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408110 c.93G>A synonymous_variant 0.29
gid 4408156 p.Leu16Arg missense_variant 1.0