TB-Profiler result

Run: ERR4819751
Summary

Run ID: ERR4819751

Sample name:

Date: 01-04-2023 16:17:08

Number of reads: 600603

Percentage reads mapped: 99.7

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776113 p.Ile790Val missense_variant 0.15
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304947 p.Asp673Asn missense_variant 0.12
fbiC 1305363 c.2433G>C synonymous_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2167745 p.Thr956Arg missense_variant 0.18
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2221940 p.Arg409* stop_gained 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726012 c.-181T>C upstream_gene_variant 0.15
pepQ 2860325 p.Tyr32His missense_variant 1.0
Rv2752c 3064603 p.Ala530Val missense_variant 0.2
Rv2752c 3065524 p.His223Arg missense_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087878 p.Glu353Asp missense_variant 0.2
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
clpC1 4039645 p.His354Asp missense_variant 0.12
clpC1 4040340 p.Gln122Pro missense_variant 0.29
embC 4240801 c.939C>T synonymous_variant 0.11
embC 4240803 p.Tyr314Phe missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244989 p.Ala586Val missense_variant 0.14
embB 4248520 p.Ser669Arg missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0