TB-Profiler result

Run: ERR4820844

Summary

Run ID: ERR4820844

Sample name:

Date: 01-04-2023 16:54:36

Number of reads: 50422

Percentage reads mapped: 58.65

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8247 p.Ile316Val missense_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 1.0
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 1.0
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 1.0
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 1.0
clpC1 4039594 p.Arg371Gly missense_variant 0.5
clpC1 4039602 p.Ala368Val missense_variant 0.5
embC 4241166 p.Thr435Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249358 p.Val949Met missense_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0