TB-Profiler result

Run: ERR4820858
Summary

Run ID: ERR4820858

Sample name:

Date: 01-04-2023 16:55:05

Number of reads: 2048184

Percentage reads mapped: 99.3

Strain: lineage4.2.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 0.98
mshA 576077 c.730C>T synonymous_variant 1.0
rpoB 761489 c.1683G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304856 c.1926C>T synonymous_variant 0.22
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 0.33
rrs 1472936 n.1091C>T non_coding_transcript_exon_variant 0.29
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.4
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.4
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.4
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.4
rrs 1472963 n.1118G>A non_coding_transcript_exon_variant 0.4
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.4
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.4
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.4
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.4
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.4
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.4
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.4
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.4
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.5
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.5
rrl 1474038 n.382_384delAGT non_coding_transcript_exon_variant 0.67
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328317 c.-844C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0