TB-Profiler result

Run: ERR4820939

Summary

Run ID: ERR4820939

Sample name:

Date: 01-04-2023 16:58:25

Number of reads: 3959176

Percentage reads mapped: 99.12

Strain: lineage4.2.2.2

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 1.0
rpoB 761489 c.1683G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.11
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.11
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.17
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.17
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.16
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.12
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.12
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.14
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.16
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.15
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.11
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.1
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.14
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.16
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.18
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.17
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.14
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.12
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.13
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.12
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.17
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.2
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.17
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.18
rrl 1475137 n.1480A>T non_coding_transcript_exon_variant 0.25
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.25
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.22
rrl 1475908 n.2251A>G non_coding_transcript_exon_variant 0.12
rrl 1476124 n.2467T>A non_coding_transcript_exon_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0