TB-Profiler result

Run: ERR4821057
Summary

Run ID: ERR4821057

Sample name:

Date: 01-04-2023 17:02:16

Number of reads: 310802

Percentage reads mapped: 46.02

Strain: lineage4

Drug-resistance: HR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.8 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.75 kanamycin, capreomycin, aminoglycosides, amikacin
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5774 c.539delT frameshift_variant 0.18
gyrA 6811 c.-491C>T upstream_gene_variant 0.29
gyrA 6841 c.-461T>C upstream_gene_variant 0.25
gyrA 6844 c.-458T>C upstream_gene_variant 0.29
gyrB 6851 p.Gln538Met missense_variant 0.29
gyrA 6859 c.-443T>C upstream_gene_variant 0.29
gyrB 6860 p.Ser541Arg missense_variant 0.29
gyrA 6869 c.-433T>C upstream_gene_variant 0.4
gyrA 6872 c.-430T>C upstream_gene_variant 0.33
gyrA 6878 c.-424T>C upstream_gene_variant 0.33
gyrA 6881 c.-421T>C upstream_gene_variant 0.33
gyrA 6898 c.-404G>C upstream_gene_variant 0.29
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575279 c.-69C>A upstream_gene_variant 0.22
rpoB 760982 c.1176G>T synonymous_variant 0.33
rpoB 760985 c.1179G>C synonymous_variant 0.33
rpoB 760988 c.1182C>G synonymous_variant 0.33
rpoB 760991 c.1185G>T synonymous_variant 0.33
rpoB 760997 c.1191G>C synonymous_variant 0.5
rpoB 761006 c.1200C>G synonymous_variant 0.5
rpoB 761015 c.1209G>C synonymous_variant 0.4
rpoB 761027 c.1221A>G synonymous_variant 0.42
rpoB 761037 c.1231T>C synonymous_variant 0.45
rpoB 761057 c.1251G>C synonymous_variant 0.38
rpoB 761064 p.Ala420Ser missense_variant 0.38
rpoB 761097 p.Ser431Cys missense_variant 0.2
rpoB 762030 p.Thr742Ser missense_variant 0.33
rpoB 762053 c.2247T>C synonymous_variant 0.25
rpoB 762062 c.2256T>C synonymous_variant 0.2
rpoB 762065 c.2259T>C synonymous_variant 0.2
rpoB 762084 p.Ala760Pro missense_variant 0.22
rpoB 762101 c.2295C>G synonymous_variant 0.22
rpoB 762114 p.Ile770Val missense_variant 0.33
rpoB 762122 p.Asp772Glu missense_variant 0.29
rpoB 762233 c.2427G>C synonymous_variant 0.6
rpoB 762245 c.2439G>C synonymous_variant 0.5
rpoB 762254 c.2448T>C synonymous_variant 0.5
rpoB 762278 c.2472C>T synonymous_variant 0.33
rpoB 762284 c.2478G>C synonymous_variant 0.4
rpoB 762293 c.2487T>C synonymous_variant 0.4
rpoB 762297 p.Leu831Met missense_variant 0.5
rpoC 762842 c.-528G>A upstream_gene_variant 0.22
rpoB 762879 p.Met1025Leu missense_variant 0.29
rpoC 762899 c.-471G>C upstream_gene_variant 0.3
rpoC 762917 c.-453C>G upstream_gene_variant 0.5
rpoC 762920 c.-450C>T upstream_gene_variant 0.55
rpoC 762923 c.-447C>G upstream_gene_variant 0.46
rpoC 762929 c.-441G>T upstream_gene_variant 0.46
rpoC 762959 c.-411G>C upstream_gene_variant 0.47
rpoC 762962 c.-408C>T upstream_gene_variant 0.5
rpoC 762983 c.-387C>T upstream_gene_variant 0.39
rpoC 762989 c.-381G>C upstream_gene_variant 0.38
rpoC 762995 c.-375G>T upstream_gene_variant 0.36
rpoB 763005 p.Cys1067Val missense_variant 0.25
rpoB 763014 p.Met1070Leu missense_variant 0.29
rpoB 763017 p.Gln1071Glu missense_variant 0.33
rpoC 763022 c.-348C>G upstream_gene_variant 0.37
rpoC 763028 c.-342T>C upstream_gene_variant 0.41
rpoB 763038 p.Thr1078Ala missense_variant 0.44
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 0.38
rpoC 763070 c.-300T>C upstream_gene_variant 0.36
rpoC 763082 c.-288C>A upstream_gene_variant 0.5
rpoC 763088 c.-282C>G upstream_gene_variant 0.44
rpoC 763115 c.-255T>C upstream_gene_variant 0.45
rpoC 763136 c.-234C>T upstream_gene_variant 0.23
rpoC 763142 c.-228C>G upstream_gene_variant 0.17
rpoC 763507 c.138G>C synonymous_variant 0.4
rpoC 763528 c.159G>T synonymous_variant 0.6
rpoC 763534 c.165T>C synonymous_variant 0.6
rpoC 763546 c.177A>G synonymous_variant 0.5
rpoC 763570 c.201G>A synonymous_variant 0.33
rpoC 763573 c.204G>C synonymous_variant 0.5
rpoC 763594 c.225C>T synonymous_variant 0.6
rpoC 763642 c.273G>C synonymous_variant 0.25
rpoC 763660 c.291T>G synonymous_variant 0.36
rpoC 763669 c.300C>G synonymous_variant 0.33
rpoC 763699 c.330G>T synonymous_variant 0.29
rpoC 763702 c.333C>G synonymous_variant 0.38
rpoC 763708 c.339G>T synonymous_variant 0.25
rpoC 763714 c.345G>C synonymous_variant 0.38
rpoC 763717 c.348T>C synonymous_variant 0.38
rpoC 763723 c.354G>C synonymous_variant 0.38
rpoC 763729 c.360G>C synonymous_variant 0.38
rpoC 763744 c.375G>C synonymous_variant 0.18
rpoC 763751 p.Ile128Val missense_variant 0.2
rpoC 763795 p.Glu142Asp missense_variant 0.2
rpoC 764338 p.Glu323Asp missense_variant 0.25
rpoC 764344 c.975C>T synonymous_variant 0.25
rpoC 764357 c.988_990delCTCinsTTG synonymous_variant 0.29
rpoC 764365 c.996C>T synonymous_variant 0.5
rpoC 764371 c.1002G>T synonymous_variant 0.4
rpoC 764377 c.1008C>G synonymous_variant 0.4
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.36
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.5
rpoC 764428 c.1059G>A synonymous_variant 0.5
rpoC 764431 c.1062G>C synonymous_variant 0.44
rpoC 764434 c.1065A>G synonymous_variant 0.44
rpoC 764435 c.1066_1068delAGGinsCGT synonymous_variant 0.44
rpoC 764441 p.Ile358Leu missense_variant 0.5
rpoC 764446 c.1077T>C synonymous_variant 0.67
rpoC 764449 c.1080G>C synonymous_variant 0.67
rpoC 764461 c.1092A>G synonymous_variant 0.67
rpoC 764485 c.1116G>C synonymous_variant 0.67
rpoC 764491 c.1122G>T synonymous_variant 0.8
rpoC 764497 c.1128A>G synonymous_variant 0.67
rpoC 764566 c.1197C>G synonymous_variant 0.29
rpoC 764575 c.1206T>G synonymous_variant 0.29
rpoC 764581 c.1212T>C synonymous_variant 0.29
rpoC 764582 p.Leu405Met missense_variant 0.29
rpoC 764602 c.1233C>T synonymous_variant 0.38
rpoC 764605 c.1236G>C synonymous_variant 0.38
rpoC 764611 c.1242G>T synonymous_variant 0.38
rpoC 764626 c.1257C>T synonymous_variant 0.5
rpoC 764632 c.1263T>C synonymous_variant 0.6
rpoC 764644 c.1275G>C synonymous_variant 0.62
rpoC 764650 c.1281G>T synonymous_variant 0.57
rpoC 764662 c.1293G>C synonymous_variant 0.29
rpoC 764677 c.1308C>G synonymous_variant 0.4
rpoC 764692 c.1323C>T synonymous_variant 0.33
rpoC 764716 c.1347G>C synonymous_variant 0.22
rpoC 764746 c.1377G>T synonymous_variant 0.33
rpoC 764752 c.1383G>C synonymous_variant 0.33
rpoC 764759 p.Asn464Asp missense_variant 0.3
rpoC 764764 c.1395T>C synonymous_variant 0.6
rpoC 764780 c.1411_1413delAGCinsTCG synonymous_variant 0.33
rpoC 764803 c.1434C>T synonymous_variant 0.33
rpoC 764809 c.1440C>T synonymous_variant 0.25
rpoC 764812 c.1443C>G synonymous_variant 0.2
rpoC 764815 c.1446A>G synonymous_variant 0.2
rpoC 764843 p.Ala492Thr missense_variant 0.18
rpoC 766318 p.Met983Ile missense_variant 0.13
rpoC 767210 p.Ala1281Thr missense_variant 0.22
rpoC 767318 c.3949T>C stop_lost&splice_region_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776759 c.1722C>T synonymous_variant 0.2
mmpL5 777586 p.Tyr299Asn missense_variant 0.14
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781658 c.99A>C synonymous_variant 0.14
rpsL 781709 c.150G>C synonymous_variant 0.11
rpsL 781715 c.156T>G synonymous_variant 0.11
rpsL 781721 c.162C>T synonymous_variant 0.12
rpsL 781749 p.Thr64Ala missense_variant 0.15
rpsL 781796 p.Met79Ile missense_variant 0.38
rpsL 781802 c.243G>C synonymous_variant 0.3
rpsL 781808 c.249C>T synonymous_variant 0.3
rpsL 781814 c.255C>T synonymous_variant 0.3
rpsL 781817 c.258G>T synonymous_variant 0.3
rpsL 781829 c.270G>C synonymous_variant 0.36
rpsL 781832 c.273T>G synonymous_variant 0.27
rpsL 781838 c.279G>C synonymous_variant 0.3
rpsL 781859 c.300T>C synonymous_variant 0.31
rpsL 781860 p.Ser101Ala missense_variant 0.23
rpsL 781865 c.306G>C synonymous_variant 0.31
rpsL 781868 c.309T>C synonymous_variant 0.29
rpsL 781871 c.312G>C synonymous_variant 0.31
fbiC 1303747 p.Thr273Ala missense_variant 1.0
embR 1416427 c.921G>A synonymous_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.29
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.22
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.22
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.2
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.18
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.25
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.25
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.18
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.35
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.26
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.62
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.75
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.67
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.67
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 1.0
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 1.0
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.5
rrs 1472337 n.492C>G non_coding_transcript_exon_variant 0.5
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.4
rrs 1472368 n.523A>G non_coding_transcript_exon_variant 0.4
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.8
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.3
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.38
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.38
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.38
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.62
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.62
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.71
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.71
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.71
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.75
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.86
rrs 1473094 n.1249T>A non_coding_transcript_exon_variant 0.86
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.86
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.83
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.83
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.6
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.6
rrs 1473127 n.1282G>A non_coding_transcript_exon_variant 1.0
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.71
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.75
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.71
rrs 1473201 n.1356A>G non_coding_transcript_exon_variant 0.62
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.62
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.6
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.6
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.8
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.71
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.83
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.8
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 0.4
rrl 1473870 n.213G>A non_coding_transcript_exon_variant 0.4
rrl 1473871 n.214T>C non_coding_transcript_exon_variant 0.4
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.4
rrl 1473887 n.230T>C non_coding_transcript_exon_variant 0.4
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.4
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.5
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.5
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.43
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.43
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.5
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.43
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.43
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.75
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 0.75
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.75
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 1.0
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.5
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.5
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.5
rrl 1474636 n.979A>G non_coding_transcript_exon_variant 0.67
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.67
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.67
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.67
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.5
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.67
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.67
rrl 1474717 n.1060A>G non_coding_transcript_exon_variant 0.67
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.67
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.67
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.67
rrl 1474751 n.1094G>A non_coding_transcript_exon_variant 0.67
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.67
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.67
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.5
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.38
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.33
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.33
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.33
rrl 1474936 n.1279C>T non_coding_transcript_exon_variant 0.5
rrl 1474938 n.1281G>A non_coding_transcript_exon_variant 0.5
rrl 1475740 n.2083G>C non_coding_transcript_exon_variant 0.8
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.8
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.8
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.8
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 0.8
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 0.8
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.8
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.83
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.83
rrl 1475788 n.2131C>G non_coding_transcript_exon_variant 0.86
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.75
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.75
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.75
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.75
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.5
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.4
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.4
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.5
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.4
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.4
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>A non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
rrl 1476288 n.2631T>C non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.5
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.44
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.44
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.55
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.77
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.75
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.67
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.6
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.6
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.5
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.5
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.4
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.4
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.6
fabG1 1673252 c.-188C>T upstream_gene_variant 0.29
rpsA 1833884 c.345delC frameshift_variant 0.17
rpsA 1833928 c.387G>C synonymous_variant 0.2
rpsA 1833949 c.408T>C synonymous_variant 0.33
rpsA 1833955 c.414G>C synonymous_variant 0.38
rpsA 1833970 c.429G>C synonymous_variant 0.3
rpsA 1833979 c.438T>C synonymous_variant 0.4
rpsA 1833991 c.450C>G synonymous_variant 0.5
rpsA 1833997 c.456G>C synonymous_variant 0.44
rpsA 1834000 c.459G>C synonymous_variant 0.56
rpsA 1834012 c.471G>T synonymous_variant 0.4
rpsA 1834015 c.474G>C synonymous_variant 0.45
rpsA 1834030 c.489C>G synonymous_variant 0.3
rpsA 1834046 p.Ile169Val missense_variant 0.2
rpsA 1834069 c.528G>C synonymous_variant 0.22
rpsA 1834210 c.669C>T synonymous_variant 0.25
rpsA 1834222 c.681T>C synonymous_variant 0.25
rpsA 1834231 c.690T>C synonymous_variant 0.27
rpsA 1834234 c.693G>C synonymous_variant 0.27
rpsA 1834246 c.705G>C synonymous_variant 0.36
rpsA 1834249 c.708T>C synonymous_variant 0.33
rpsA 1834255 c.714C>G synonymous_variant 0.33
rpsA 1834261 c.720A>G synonymous_variant 0.38
rpsA 1834264 c.723G>C synonymous_variant 0.38
rpsA 1834294 c.753G>T synonymous_variant 0.45
rpsA 1834298 p.Gln253Glu missense_variant 0.38
rpsA 1834303 c.762T>C synonymous_variant 0.43
rpsA 1834306 c.765T>C synonymous_variant 0.5
rpsA 1834307 p.Asp256Gln missense_variant 0.5
rpsA 1834312 c.771G>A synonymous_variant 0.5
rpsA 1834348 c.807T>C synonymous_variant 0.6
rpsA 1834354 c.813G>T synonymous_variant 0.6
rpsA 1834357 c.816T>C synonymous_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102781 p.Asn88Asp missense_variant 0.22
ndh 2102833 c.210G>T synonymous_variant 0.12
PPE35 2168864 c.1749G>T synonymous_variant 0.4
Rv1979c 2223233 c.-69G>C upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289551 c.-310C>A upstream_gene_variant 0.2
eis 2715029 p.Ala102Thr missense_variant 0.5
folC 2747008 c.591C>A synonymous_variant 0.2
thyX 3068062 c.-117A>G upstream_gene_variant 0.18
thyA 3073969 p.Ala168Val missense_variant 0.22
ald 3087484 p.Ala222Val missense_variant 0.2
whiB7 3568629 c.51T>A synonymous_variant 0.17
alr 3840751 p.Glu224Lys missense_variant 0.2
rpoA 3877920 c.588G>C synonymous_variant 0.33
rpoA 3877926 p.Leu194Val missense_variant 0.33
clpC1 4038588 p.Arg706His missense_variant 0.25
clpC1 4038662 c.2043T>C synonymous_variant 0.25
clpC1 4039550 c.1155G>C synonymous_variant 0.18
clpC1 4039554 p.Thr384Asn missense_variant 0.17
clpC1 4039556 p.Ala383Val missense_variant 0.17
clpC1 4039570 p.Met379Leu missense_variant 0.22
clpC1 4039574 c.1131G>C synonymous_variant 0.25
clpC1 4039577 c.1128T>C synonymous_variant 0.25
clpC1 4039588 p.Ser373Thr missense_variant 0.25
clpC1 4039589 c.1116G>C synonymous_variant 0.25
clpC1 4039592 c.1113G>C synonymous_variant 0.2
clpC1 4039601 c.1104G>A synonymous_variant 0.3
clpC1 4039610 c.1095G>T synonymous_variant 0.3
clpC1 4039616 c.1089G>C synonymous_variant 0.33
clpC1 4039622 c.1083C>T synonymous_variant 0.25
clpC1 4039714 p.Tyr331His missense_variant 0.6
clpC1 4039724 c.981A>G synonymous_variant 0.5
clpC1 4039742 c.963C>T synonymous_variant 0.4
clpC1 4039748 c.957G>C synonymous_variant 0.4
clpC1 4039751 c.954A>G synonymous_variant 0.4
clpC1 4039757 c.948A>G synonymous_variant 0.4
clpC1 4039766 c.939T>C synonymous_variant 0.4
clpC1 4039769 c.936C>G synonymous_variant 0.4
clpC1 4039773 p.Lys311Met missense_variant 0.4
clpC1 4039778 c.927A>G synonymous_variant 0.4
clpC1 4039787 c.918G>C synonymous_variant 0.36
clpC1 4039790 c.915C>G synonymous_variant 0.3
clpC1 4039814 c.891C>G synonymous_variant 0.2
clpC1 4039817 c.888A>T synonymous_variant 0.18
clpC1 4039820 c.885T>C synonymous_variant 0.18
clpC1 4039916 c.789T>C synonymous_variant 0.12
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.17
clpC1 4039934 c.771G>C synonymous_variant 0.17
clpC1 4039946 c.759A>G synonymous_variant 0.2
clpC1 4039949 c.756G>C synonymous_variant 0.2
clpC1 4039952 c.753T>C synonymous_variant 0.2
clpC1 4039955 c.750G>C synonymous_variant 0.25
clpC1 4039979 c.726C>G synonymous_variant 0.22
clpC1 4039994 p.Glu237Asp missense_variant 0.22
embC 4239717 c.-146C>T upstream_gene_variant 0.14
embC 4239745 c.-118C>A upstream_gene_variant 0.13
embC 4239970 c.108G>T synonymous_variant 0.13
embC 4241284 c.1422G>A synonymous_variant 0.22
embC 4241644 c.1782G>T synonymous_variant 0.5
embC 4241998 c.2136G>T synonymous_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242784 c.-449G>T upstream_gene_variant 0.2
embA 4243965 p.Arg245Trp missense_variant 0.22
embA 4244003 c.771G>A synonymous_variant 0.33
embB 4248077 p.Asn522Tyr missense_variant 0.18
embB 4248673 c.2160G>A synonymous_variant 0.14
embB 4248810 p.Pro766Gln missense_variant 0.29
aftB 4267170 p.Gln556Arg missense_variant 0.12
ethA 4326074 p.Leu467His missense_variant 0.22
ethR 4326700 c.-849C>T upstream_gene_variant 0.25
ethR 4327803 p.Met85Ile missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0