TB-Profiler result

Run: ERR4821832
Summary

Run ID: ERR4821832

Sample name:

Date: 01-04-2023 17:28:33

Number of reads: 67811

Percentage reads mapped: 97.84

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.97
lineage4.9 Euro-American (H37Rv-like) T1 None 0.94
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575907 p.Ala187Val missense_variant 1.0
rpoB 760028 c.222C>A synonymous_variant 1.0
rpoB 761706 p.Asp634Tyr missense_variant 0.4
mmpL5 778420 p.Arg21* stop_gained 0.67
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
atpE 1461210 p.Thr56Ala missense_variant 0.4
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673315 c.-125A>G upstream_gene_variant 0.67
katG 2155862 p.Met84Leu missense_variant 1.0
PPE35 2167813 p.Gln934* stop_gained 0.4
PPE35 2167926 p.Leu896Ser missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568614 c.66C>A synonymous_variant 0.67
Rv3236c 3612398 p.Ala240Val missense_variant 0.67
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4248183 p.Met557Thr missense_variant 0.67
embB 4249441 c.2928A>G synonymous_variant 0.5
embB 4249444 c.2931T>C synonymous_variant 0.5
embB 4249469 p.Leu986Met missense_variant 0.4
embB 4249486 c.2973T>G synonymous_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0