TB-Profiler result

Run: ERR4822202
Summary

Run ID: ERR4822202

Sample name:

Date: 01-04-2023 17:41:43

Number of reads: 1048011

Percentage reads mapped: 99.55

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 759821 c.15C>A synonymous_variant 0.11
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775941 p.Gly847Val missense_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1407201 p.Val47Gly missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155428 c.684C>A synonymous_variant 0.11
PPE35 2170036 p.Val193Met missense_variant 0.15
PPE35 2170273 p.Arg114Cys missense_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2859921 c.498C>A synonymous_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086884 p.Gly22Asp missense_variant 0.11
ald 3086904 p.Arg29Cys missense_variant 0.12
fbiD 3339197 p.Ala27Val missense_variant 0.15
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474144 p.Trp46Cys missense_variant 0.12
Rv3236c 3612169 p.Glu316Asp missense_variant 0.11
fbiA 3641308 p.Ala256Thr missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4244279 c.1047G>T synonymous_variant 0.15
embB 4249408 c.2895G>A synonymous_variant 1.0
embB 4249678 c.3165C>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0