TB-Profiler result

Run: ERR4822217
Summary

Run ID: ERR4822217

Sample name:

Date: 01-04-2023 17:42:24

Number of reads: 2168110

Percentage reads mapped: 98.76

Strain: lineage4.3.4.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.4 Euro-American (LAM) LAM RD174 1.0
lineage4.3.4.1 Euro-American (LAM) LAM1;LAM2 RD174 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406737 p.Thr202Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.33
rrs 1473263 n.1418A>G non_coding_transcript_exon_variant 0.33
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.33
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.25
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.25
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.25
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.25
rrl 1473530 n.-128G>C upstream_gene_variant 0.11
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.4
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.67
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.5
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.5
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.67
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.67
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 1.0
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 1.0
rrl 1474928 n.1271C>T non_coding_transcript_exon_variant 1.0
rrl 1474933 n.1276A>G non_coding_transcript_exon_variant 1.0
rrl 1474934 n.1277C>T non_coding_transcript_exon_variant 1.0
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.67
rrl 1476688 n.3031C>A non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2222854 p.Ile104Thr missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
clpC1 4039991 c.714G>A synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0