TB-Profiler result

Run: ERR4829700
Summary

Run ID: ERR4829700

Sample name:

Date: 01-04-2023 19:38:16

Number of reads: 3685661

Percentage reads mapped: 98.73

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.17
mshA 576482 p.Val379Leu missense_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472124 n.279C>A non_coding_transcript_exon_variant 0.11
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.14
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.11
rrs 1472823 n.978C>A non_coding_transcript_exon_variant 0.11
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.11
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474534 n.877G>C non_coding_transcript_exon_variant 0.13
rrl 1474661 n.1004G>A non_coding_transcript_exon_variant 0.1
rrl 1475013 n.1356G>T non_coding_transcript_exon_variant 0.15
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.1
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.1
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.1
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.1
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102055 p.Pro330Ser missense_variant 1.0
PPE35 2168076 p.Thr846Met missense_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
alr 3841256 c.165C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.26
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0