TB-Profiler result

Run: ERR4831315
Summary

Run ID: ERR4831315

Sample name:

Date: 01-04-2023 20:50:38

Number of reads: 5929077

Percentage reads mapped: 99.71

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303747 p.Thr273Ala missense_variant 1.0
embR 1417346 c.1delA frameshift_variant&start_lost 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.39
rpoA 3878613 c.-106A>C upstream_gene_variant 0.18
rpoA 3878618 c.-111A>C upstream_gene_variant 0.15
rpoA 3878630 c.-123G>C upstream_gene_variant 0.14
rpoA 3878637 c.-130G>C upstream_gene_variant 0.12
rpoA 3878641 c.-134C>G upstream_gene_variant 0.16
clpC1 4039057 p.Ile550Val missense_variant 0.23
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4245533 c.-981C>T upstream_gene_variant 1.0
embB 4246151 c.-363A>G upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.44
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0