TB-Profiler result

Run: ERR495087
Summary

Run ID: ERR495087

Sample name:

Date: 01-04-2023 21:37:43

Number of reads: 581810

Percentage reads mapped: 99.71

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491308 p.Ala176Thr missense_variant 0.25
fgd1 491312 p.Gly177Ala missense_variant 0.2
fgd1 491742 c.960T>C synonymous_variant 0.75
mshA 575907 p.Ala187Val missense_variant 1.0
ccsA 620625 p.Ile245Met missense_variant 1.0
ccsA 620751 p.Trp287Cys missense_variant 0.22
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 765189 p.Pro607Gln missense_variant 0.25
rpoC 767041 c.3672G>A synonymous_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775675 p.Trp936Arg missense_variant 0.22
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
embR 1416372 p.Ser326Gly missense_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101697 p.Ala449Val missense_variant 0.13
kasA 2518417 c.303G>T synonymous_variant 0.25
eis 2714846 p.Val163Ile missense_variant 1.0
Rv2752c 3065504 p.Asp230Tyr missense_variant 0.5
Rv3083 3448985 p.Gly161Asp missense_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475093 p.Gly363Trp missense_variant 0.18
embC 4239736 c.-127C>A upstream_gene_variant 0.13
embC 4241375 p.Ala505Thr missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4246069 p.Pro946Gln missense_variant 0.18
embB 4248115 c.1602C>T synonymous_variant 1.0
aftB 4267647 p.Asp397Gly missense_variant 1.0
ethR 4327643 p.Thr32Ile missense_variant 0.4
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0