TB-Profiler result

Run: ERR495141
Summary

Run ID: ERR495141

Sample name:

Date: 01-04-2023 21:40:07

Number of reads: 3642794

Percentage reads mapped: 99.76

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575761 c.414C>T synonymous_variant 1.0
rpoB 759814 p.Asp3Gly missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 778869 p.Leu13Ile missense_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781502 c.-58G>T upstream_gene_variant 1.0
embR 1416625 c.723C>A synonymous_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168780 c.1833C>T synonymous_variant 0.13
Rv1979c 2221729 p.Ser479Asn missense_variant 0.22
Rv1979c 2221730 p.Ser479Gly missense_variant 0.22
Rv1979c 2221733 p.Pro478Ala missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289662 c.-421G>T upstream_gene_variant 0.15
ald 3086750 c.-70A>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0