TB-Profiler result

Run: ERR552521
Summary

Run ID: ERR552521

Sample name:

Date: 02-08-2023 08:50:32

Number of reads: NA

Percentage reads mapped: NA

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 619831 c.-60T>G upstream_gene_variant 0.17
rpoB 761359 p.Val518Ala missense_variant 0.12
rpoC 766242 p.Thr958Ile missense_variant 1.0
rpoC 767139 p.Leu1257Gln missense_variant 0.12
rpoC 767304 p.Tyr1312Phe missense_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460993 c.-52C>T upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101724 p.Thr440Met missense_variant 0.14
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726089 c.-104C>T upstream_gene_variant 0.12
Rv3236c 3612180 p.Ala313Ser missense_variant 0.12
alr 3840764 c.657G>C synonymous_variant 1.0
rpoA 3877993 p.Leu172Pro missense_variant 0.1
panD 4044203 p.Thr27Ser missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249094 p.Ala861Thr missense_variant 1.0
aftB 4268672 c.165C>T synonymous_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0