TB-Profiler result

Run: ERR552622
Summary

Run ID: ERR552622

Sample name:

Date: 18-08-2022 09:21:35

Number of reads: 466698

Percentage reads mapped: 99.58

Strain: lineage4.1.1.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.3 Euro-American (X-type) X1;X3 RD193 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6847 c.-455C>T upstream_gene_variant 0.12
gyrB 6932 p.Gln565Lys missense_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8310 c.1009C>T synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781435 c.-125G>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 0.96
rrs 1472789 n.944G>T non_coding_transcript_exon_variant 0.1
inhA 1673508 c.-694A>G upstream_gene_variant 0.2
pncA 2289657 c.-416G>A upstream_gene_variant 0.15
folC 2747129 p.Ala157Val missense_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086987 p.Gln56His missense_variant 0.15
embC 4240904 p.Thr348Pro missense_variant 0.12
embB 4249408 c.2895G>A synonymous_variant 1.0
gid 4407798 c.405G>T synonymous_variant 1.0
gid 4408340 c.-138C>T upstream_gene_variant 0.11