TB-Profiler result

Run: ERR553093
Summary

Run ID: ERR553093

Sample name:

Date: 15-08-2022 10:50:03

Number of reads: 579053

Percentage reads mapped: 99.68

Strain: lineage4.6.2.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.2 Euro-American T;LAM RD726 0.99
lineage4.6.2.2 Euro-American (Cameroon) LAM10-CAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776789 c.1692C>T synonymous_variant 0.12
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801019 c.218_220delCCG disruptive_inframe_deletion 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 1.0
rpsA 1833651 p.Asp37Ala missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155286 p.His276Asn missense_variant 0.13
Rv1979c 2221746 c.1416_1418dupCCG disruptive_inframe_insertion 1.0
Rv1979c 2222454 c.711G>A synonymous_variant 0.13
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3064969 p.Lys408Arg missense_variant 0.12
Rv3083 3448567 p.His22Asp missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878234 p.Pro92Ser missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242801 p.Pro980Leu missense_variant 0.12
aftB 4267272 p.Lys522Arg missense_variant 1.0
ethR 4326739 c.-810G>C upstream_gene_variant 1.0
ethA 4328004 c.-531C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338648 c.-128_-127insT upstream_gene_variant 1.0
gid 4407797 p.Ser136Thr missense_variant 0.1
gid 4407980 p.Pro75Thr missense_variant 1.0