TB-Profiler result

Run: ERR5908163
Summary

Run ID: ERR5908163

Sample name:

Date: 02-04-2023 00:51:40

Number of reads: 833899

Percentage reads mapped: 99.53

Strain: lineage4.1.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
lineage4.1.1.2 Euro-American (X-type) X1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7033 c.-269G>A upstream_gene_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.28
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302814 c.-117C>T upstream_gene_variant 1.0
Rv1258c 1406362 p.Pro327Ser missense_variant 0.12
atpE 1461052 p.Pro3Leu missense_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473078 n.1233G>A non_coding_transcript_exon_variant 0.29
rrl 1473562 n.-96G>T upstream_gene_variant 0.22
rrl 1474379 n.722G>A non_coding_transcript_exon_variant 0.29
rrl 1476093 n.2436A>G non_coding_transcript_exon_variant 0.5
rrl 1476564 n.2907G>T non_coding_transcript_exon_variant 0.33
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169671 c.942C>T synonymous_variant 0.25
PPE35 2169765 p.Gly283Val missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
thyA 3073847 p.Tyr209His missense_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086867 c.48G>A synonymous_variant 1.0
Rv3083 3449340 c.837C>A synonymous_variant 0.12
Rv3083 3449787 c.1284C>T synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878682 c.-176delG upstream_gene_variant 0.13
embC 4241572 c.1710C>T synonymous_variant 1.0
embA 4242409 c.-824G>T upstream_gene_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243833 p.Ala201Thr missense_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.24
embB 4246930 p.Gln139His missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
ethA 4327510 c.-37G>T upstream_gene_variant 0.15
whiB6 4338595 c.-75delG upstream_gene_variant 1.0