Run ID: ERR5908228
Sample name:
Date: 2024-04-15T02:15:41.507519
Number of reads: 4424249
Percentage reads mapped: 81.36
Median coverage: 126.0
Strain: lineage4.3.3
Spoligotype:
Drug-resistance: RR-TB
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.3 | Euro-American (LAM) | None | 0.98 |
lineage4 | Euro-American | None | 0.96 |
lineage4.3.3 | Euro-American (LAM) | RD115 | 0.98 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | rpoB | c.1327_1329delTTGinsCC | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
isoniazid | ||||
ethambutol | embB | p.His312Arg | Mutation from literature | |
pyrazinamide | ||||
streptomycin | rrs | n.462C>T | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | fbiC | c.1039_1041delGTTinsAC | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rpoB | 761133 | c.1327_1329delTTGinsCC | frameshift_variant&missense_variant | 0.2 | rifampicin | Assoc w R - Interim | Expert rule: Non-silent variants in RRDR of rpoB |
fbiC | 1303969 | c.1039_1041delGTTinsAC | frameshift_variant&missense_variant | 0.21 | pretomanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance |
delamanid | Assoc w R - Interim | Confers DLM-PMD cross-resistance | |||||
rrs | 1472307 | n.462C>T | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance | Mutation from literature |
embB | 4247448 | p.His312Arg | missense_variant | 0.2 | ethambutol | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 636 | c.636C>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 705 | c.705A>G | synonymous_variant | 0.16 | isoniazid | |
dnaA | 708 | c.708T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 741 | c.741T>C | synonymous_variant | 0.22 | isoniazid | Not assoc w R - Interim |
dnaA | 750 | c.750C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 756 | c.756T>C | synonymous_variant | 0.22 | isoniazid | |
dnaA | 771 | c.771A>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 777 | c.777A>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 786 | c.786C>T | synonymous_variant | 0.21 | isoniazid | |
dnaA | 795 | c.795A>C | synonymous_variant | 0.2 | isoniazid | Not assoc w R - Interim |
dnaA | 805 | c.805T>C | synonymous_variant | 0.24 | isoniazid | |
dnaA | 813 | c.813C>T | synonymous_variant | 0.26 | isoniazid | |
dnaA | 822 | c.822A>G | synonymous_variant | 0.26 | isoniazid | |
dnaA | 828 | c.828T>C | synonymous_variant | 0.27 | isoniazid | Not assoc w R - Interim |
dnaA | 831 | c.831A>G | synonymous_variant | 0.27 | isoniazid | |
dnaA | 837 | c.837A>G | synonymous_variant | 0.25 | isoniazid | |
dnaA | 840 | c.840G>A | synonymous_variant | 0.23 | isoniazid | |
dnaA | 843 | c.843T>C | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 846 | c.846T>C | synonymous_variant | 0.23 | isoniazid | |
dnaA | 849 | c.849A>G | synonymous_variant | 0.23 | isoniazid | |
dnaA | 1152 | c.1152A>G | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1153 | c.1153T>C | synonymous_variant | 0.17 | isoniazid | |
dnaA | 1161 | c.1161A>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1164 | c.1164A>C | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1167 | c.1167A>G | synonymous_variant | 0.18 | isoniazid | Not assoc w R - Interim |
dnaA | 1176 | c.1176A>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1177 | p.Ala393Ser | missense_variant | 0.18 | isoniazid | |
dnaA | 1191 | c.1191T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1197 | c.1197T>G | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1204 | c.1204C>T | synonymous_variant | 0.19 | isoniazid | |
dnaA | 1220 | p.Asn407Ser | missense_variant | 0.19 | isoniazid | |
dnaA | 1230 | c.1230A>G | synonymous_variant | 0.24 | isoniazid | |
dnaA | 1242 | c.1242G>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.23 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.27 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.25 | isoniazid | |
dnaA | 1287 | c.1287A>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1290 | c.1290G>A | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1293 | c.1293T>G | synonymous_variant | 0.21 | isoniazid | |
dnaA | 1302 | c.1302C>G | synonymous_variant | 0.22 | isoniazid | |
dnaA | 1314 | c.1314A>G | synonymous_variant | 0.16 | isoniazid | |
gyrB | 6214 | c.975G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6217 | c.978G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6223 | c.984G>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Lys | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6253 | c.1014G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6274 | c.1035C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6295 | c.1056A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6298 | c.1059C>T | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6299 | c.1060C>T | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6319 | c.1080G>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 6325 | c.-977C>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6706 | c.-596G>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6730 | c.-572A>G | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6742 | c.-560A>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6760 | c.-542G>C | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6778 | c.-524C>T | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6793 | c.1554T>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6797 | p.Gly520Thr | missense_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6824 | c.1585C>T | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6841 | c.1602T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6844 | c.-458T>G | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6853 | c.-449A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6856 | c.1617T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6859 | c.1620T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6862 | c.1623C>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6878 | c.1639T>C | synonymous_variant | 0.26 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6881 | c.1642T>C | synonymous_variant | 0.27 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6904 | c.-398C>G | upstream_gene_variant | 0.29 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6910 | c.-392G>A | upstream_gene_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6911 | p.Asn558His | missense_variant | 0.28 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6919 | c.1680T>C | synonymous_variant | 0.3 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6925 | c.-377T>C | upstream_gene_variant | 0.27 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6931 | c.-371A>C | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6934 | c.-368A>G | upstream_gene_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6937 | c.1698G>A | synonymous_variant | 0.24 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6949 | c.-353A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6952 | c.1713C>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6955 | c.-347G>A | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6967 | c.-335T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6970 | c.-332C>T | upstream_gene_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6973 | c.-329G>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7427 | c.126G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7442 | c.141G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7451 | c.150C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7457 | c.156T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7472 | c.171T>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 7475 | c.174A>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7480 | p.Phe60Tyr | missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7484 | c.183T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7487 | c.186C>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7490 | c.189C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7517 | c.216G>A | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7523 | c.222C>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7532 | c.231T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7538 | c.237G>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7541 | c.240C>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7715 | c.414G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7730 | p.Arg143Ser | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7760 | c.459C>T | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7763 | c.462T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7799 | c.498A>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7835 | c.534A>G | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8040 | p.Gly247Ser | missense_variant | 0.92 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 8090 | c.789C>G | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8111 | c.810G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8156 | c.855T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8168 | c.867A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8174 | c.873C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8177 | c.876A>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8198 | c.897T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8207 | c.906T>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8219 | c.918T>C | synonymous_variant | 0.23 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8225 | c.924T>C | synonymous_variant | 0.23 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8234 | c.933T>G | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8235 | c.934_936delTTAinsCG | frameshift_variant&missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8253 | p.Ile318Leu | missense_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8264 | c.963T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8267 | c.966G>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8270 | c.969G>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8294 | c.993T>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8324 | c.1023T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8339 | c.1038A>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8342 | c.1041G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8351 | c.1050C>T | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8366 | c.1065G>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8375 | c.1074G>C | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 8391 | c.1090_1092delTATinsCC | frameshift_variant&missense_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8399 | c.1098T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8442 | c.1141C>T | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8471 | c.1170T>C | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8480 | c.1179C>T | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8498 | c.1197C>T | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8504 | c.1203G>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8537 | c.1236G>A | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8546 | c.1245T>C | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8557 | p.Ala419Asp | missense_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8624 | c.1323G>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8627 | c.1326C>G | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8636 | c.1335A>C | synonymous_variant | 0.19 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8642 | c.1341A>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8645 | c.1344C>G | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8672 | c.1371A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8693 | c.1392T>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8699 | c.1398A>G | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8711 | c.1410A>C | synonymous_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8714 | c.1413A>G | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8717 | c.1416C>G | synonymous_variant | 0.2 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8720 | c.1419G>A | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8726 | c.1425G>A | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8729 | c.1428T>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8732 | c.1431G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8735 | c.1434C>T | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8747 | c.1446A>G | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8756 | c.1455A>G | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8762 | c.1461G>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8765 | p.Asp488Glu | missense_variant | 0.17 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8767 | p.Arg489Lys | missense_variant | 0.18 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 8779 | p.Asp493Ala | missense_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8897 | c.1596T>C | synonymous_variant | 0.17 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8903 | c.1602T>C | synonymous_variant | 0.21 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8915 | c.1614A>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8918 | c.1617C>G | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8939 | c.1638T>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8942 | c.1641G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8945 | c.1644G>C | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8946 | c.1645_1647delTTGinsCC | frameshift_variant&missense_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8951 | c.1650G>A | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8966 | c.1665C>G | synonymous_variant | 0.25 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 8967 | p.Ala556Arg | missense_variant | 0.24 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8987 | c.1686C>G | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8990 | c.1689C>G | synonymous_variant | 0.31 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8996 | c.1695T>C | synonymous_variant | 0.3 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 8998 | p.Leu566Trp | missense_variant | 0.3 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9023 | c.1722A>C | synonymous_variant | 0.28 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9029 | c.1728T>C | synonymous_variant | 0.26 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9032 | c.1731T>C | synonymous_variant | 0.25 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9035 | c.1734G>C | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | ||||||
gyrA | 9204 | p.Ser635Thr | missense_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9252 | p.Val651Ile | missense_variant | 0.14 | levofloxacin | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
gyrA | 9275 | c.1974G>A | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9278 | c.1977G>C | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9291 | c.1990C>T | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9296 | c.1995T>C | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9304 | p.Gly668Glu | missense_variant | 1.0 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9311 | c.2010C>T | synonymous_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9323 | c.2022C>G | synonymous_variant | 0.22 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9335 | c.2034G>C | synonymous_variant | 0.22 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9345 | c.2044A>C | synonymous_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9374 | c.2073G>C | synonymous_variant | 0.18 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 9377 | c.2076A>G | synonymous_variant | 0.18 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 9383 | c.2082T>C | synonymous_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
fgd1 | 491083 | p.Val101Ile | missense_variant | 0.14 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491091 | c.309T>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491094 | c.312C>G | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491106 | c.324T>C | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491121 | c.339A>G | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491137 | p.Glu119Gln | missense_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491144 | p.Ala121Glu | missense_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491166 | c.384G>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491181 | c.399T>C | synonymous_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491191 | p.Gly137Arg | missense_variant | 0.23 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491196 | c.414A>G | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491202 | c.420G>C | synonymous_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491203 | p.Gln141Glu | missense_variant | 0.22 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491212 | p.Ser144Arg | missense_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491217 | c.435T>C | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491232 | c.450T>C | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491241 | p.Asp153Glu | missense_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491244 | c.462T>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fgd1 | 491259 | c.477T>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
ccsA | 620269 | p.Val127Ile | missense_variant | 0.14 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620288 | p.Arg133Gln | missense_variant | 0.14 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620295 | c.405G>C | synonymous_variant | 0.17 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620307 | c.417C>G | synonymous_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620349 | c.459A>G | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.16 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620646 | c.756G>A | synonymous_variant | 0.15 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620661 | c.771C>G | synonymous_variant | 0.16 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620703 | c.813G>C | synonymous_variant | 0.2 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620710 | p.Val274Met | missense_variant | 0.16 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
Rv0565c | 657242 | p.Glu77Lys | missense_variant | 0.17 | ethionamide | |
Rv0565c | 657259 | p.Tyr71Phe | missense_variant | 0.19 | ethionamide | |
Rv0565c | 657261 | c.210C>G | synonymous_variant | 0.2 | ethionamide | |
Rv0565c | 657264 | c.207T>C | synonymous_variant | 0.22 | ethionamide | |
Rv0565c | 657267 | c.204G>C | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657291 | c.180C>G | synonymous_variant | 0.21 | ethionamide | |
Rv0565c | 657300 | c.171C>T | synonymous_variant | 0.2 | ethionamide | |
Rv0565c | 657641 | c.-171C>G | upstream_gene_variant | 0.17 | ethionamide | |
Rv0565c | 657649 | c.-179G>A | upstream_gene_variant | 0.18 | ethionamide | |
Rv0565c | 657678 | c.-209_-208delAAinsGG | upstream_gene_variant | 0.2 | ethionamide | |
Rv0565c | 657689 | c.-220_-219delCAinsAG | upstream_gene_variant | 0.18 | ethionamide | |
Rv0565c | 657701 | c.-231C>G | upstream_gene_variant | 0.18 | ethionamide | |
Rv0565c | 657719 | c.-249C>G | upstream_gene_variant | 0.16 | ethionamide | |
Rv0565c | 657734 | c.-264T>C | upstream_gene_variant | 0.17 | ethionamide | |
hadA | 732346 | c.417T>C | synonymous_variant | 0.16 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.2 | isoniazid | |
hadA | 732389 | p.Ser154Thr | missense_variant | 0.22 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.22 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.2 | isoniazid | |
nusG | 734442 | c.189G>A | synonymous_variant | 0.15 | rifampicin | |
nusG | 734457 | c.204C>G | synonymous_variant | 0.16 | rifampicin | |
nusG | 734472 | c.219T>C | synonymous_variant | 0.17 | rifampicin | |
nusG | 734475 | c.222T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
nusG | 734481 | c.228C>G | synonymous_variant | 0.23 | rifampicin | |
nusG | 734499 | c.246G>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734532 | c.279A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
nusG | 734541 | c.288A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
nusG | 734559 | c.306T>C | synonymous_variant | 0.22 | rifampicin | |
nusG | 734580 | c.327T>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
nusG | 734595 | c.342C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
nusG | 734596 | c.343T>C | synonymous_variant | 0.2 | rifampicin | |
nusG | 734610 | c.357C>G | synonymous_variant | 0.16 | rifampicin | |
nusG | 734625 | c.372T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 760235 | c.429T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760253 | c.447T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoB | 760283 | c.477G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760337 | c.531C>G | synonymous_variant | 0.24 | rifampicin | |
rpoB | 760340 | c.534G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.27 | rifampicin | Uncertain significance |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760418 | c.612G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760869 | p.Val355Ile | missense_variant | 0.16 | rifampicin | Uncertain significance |
rpoB | 760886 | c.1080A>G | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760919 | c.1113C>G | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760925 | c.1119T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 760928 | c.1122G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 760934 | c.1128C>T | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760946 | c.1140A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760970 | c.1164G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 760982 | c.1176G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760985 | c.1179G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 760991 | c.1185G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761015 | c.1209G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761021 | c.1215G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761027 | c.1221A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761036 | c.1230G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761037 | c.1231T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761051 | c.1245G>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761054 | c.1248G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761057 | c.1251G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761060 | c.1254C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761063 | c.1257C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 761097 | c.1291_1292delAGinsTC | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761102 | c.1296A>G | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761168 | c.1362C>G | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761171 | c.1365C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoB | 761183 | c.1377T>G | synonymous_variant | 0.26 | rifampicin | |
rpoB | 761189 | c.1383T>G | synonymous_variant | 0.27 | rifampicin | |
rpoB | 761222 | c.1416G>C | synonymous_variant | 0.25 | rifampicin | |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoB | 761285 | c.1479G>A | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761354 | c.1548C>A | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.16 | rifampicin | |
rpoB | 761373 | p.Val523His | missense_variant | 0.16 | rifampicin | |
rpoB | 761414 | c.1608A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761423 | c.1617T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761435 | c.1629T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761437 | p.Ala544Asp | missense_variant | 0.16 | rifampicin | |
rpoB | 761439 | p.Asp545Asn | missense_variant | 0.16 | rifampicin | |
rpoB | 761444 | c.1638T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761447 | c.1641C>G | synonymous_variant | 0.16 | rifampicin | |
rpoB | 761452 | p.Val549Ala | missense_variant | 0.16 | rifampicin | |
rpoB | 761457 | c.1651_1653delCCGinsGC | frameshift_variant&missense_variant | 0.16 | rifampicin | |
rpoB | 761462 | c.1656C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761492 | c.1686G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 761510 | c.1704T>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 761531 | c.1725C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761537 | c.1731C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761570 | c.1764T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761573 | c.1767C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761579 | c.1773G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761606 | c.1800C>G | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761675 | c.1869G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761690 | c.1884G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761714 | c.1908C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761735 | c.1929C>G | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761747 | c.1941G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761750 | c.1944G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761765 | c.1959T>C | synonymous_variant | 0.19 | rifampicin | |
rpoB | 761772 | p.His656Ala | missense_variant | 0.18 | rifampicin | |
rpoB | 761778 | p.Asn658Asp | missense_variant | 0.19 | rifampicin | |
rpoB | 761791 | p.Arg662His | missense_variant | 0.22 | rifampicin | |
rpoB | 761813 | c.2007T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761815 | p.Ala670Glu | missense_variant | 0.21 | rifampicin | |
rpoB | 761834 | c.2028T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761847 | p.Cys681Ser | missense_variant | 0.2 | rifampicin | |
rpoB | 761852 | c.2046C>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761858 | c.2052G>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761864 | c.2058G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 761873 | c.2067A>G | synonymous_variant | 0.21 | rifampicin | |
rpoB | 761885 | c.2079T>C | synonymous_variant | 0.2 | rifampicin | |
rpoB | 761891 | c.2085G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 761999 | c.2193G>C | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762008 | c.2202C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 762014 | c.2208C>T | synonymous_variant | 0.21 | rifampicin | |
rpoB | 762017 | c.2211A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoB | 762053 | c.2247T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762062 | c.2256T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762101 | c.2295C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762114 | p.Ile770Val | missense_variant | 0.18 | rifampicin | Uncertain significance |
rpoB | 762140 | c.2334G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762143 | c.2337T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762149 | c.2343G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762167 | c.2361T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762176 | c.2370T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762185 | c.2379G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 762218 | c.2412T>G | synonymous_variant | 0.19 | rifampicin | |
rpoB | 762254 | c.2448T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoB | 762266 | c.2460T>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 762284 | c.2478G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762317 | c.2511A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.16 | rifampicin | |
rpoB | 762362 | p.Glu852Asp | missense_variant | 0.16 | rifampicin | |
rpoB | 762369 | c.2563T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 762380 | c.-990T>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 762395 | c.-975G>C | upstream_gene_variant | 0.15 | rifampicin | |
rpoC | 762410 | c.-960T>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoB | 762416 | c.2610A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoB | 762470 | c.2664G>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 762551 | c.-819C>T | upstream_gene_variant | 0.13 | rifampicin | |
rpoB | 762929 | c.3123G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.29 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 763028 | c.3222T>C | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763031 | c.3225T>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763034 | c.3228C>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoB | 763040 | c.3234C>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoB | 763070 | c.3264T>C | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763076 | c.-294C>G | upstream_gene_variant | 0.31 | rifampicin | |
rpoB | 763085 | c.3279C>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.25 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.22 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763169 | c.-201A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCC | upstream_gene_variant | 0.17 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763220 | c.-150G>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 763402 | c.33C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763411 | c.42T>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 763414 | c.45T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763441 | c.72C>G | synonymous_variant | 0.28 | rifampicin | |
rpoC | 763444 | c.75T>C | synonymous_variant | 0.28 | rifampicin | Not assoc w R - Interim |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763468 | c.99G>C | synonymous_variant | 0.3 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoC | 763546 | c.177A>G | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763633 | c.264T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763642 | c.273G>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 763658 | c.289_291delCTTinsTG | frameshift_variant&missense_variant | 0.28 | rifampicin | |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763708 | c.339G>A | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763709 | c.340C>T | synonymous_variant | 0.16 | rifampicin | |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763735 | c.366G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763780 | c.411C>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.2 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.2 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763919 | c.550C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 763945 | c.576T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763960 | c.591T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763967 | p.Gly200Ser | missense_variant | 0.17 | rifampicin | |
rpoC | 763978 | c.609C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764011 | c.642T>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 764024 | c.655T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764040 | p.Ser224Asn | missense_variant | 0.19 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764059 | c.690G>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764161 | c.792G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764188 | c.819A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764195 | p.Ser276Gln | missense_variant | 0.22 | rifampicin | |
rpoC | 764203 | c.834G>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764206 | c.837T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764257 | c.888G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764266 | c.897T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764269 | c.900G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 764278 | c.909A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764282 | c.913_915delTCGinsAGC | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764365 | c.996C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764431 | c.1062G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764539 | c.1170C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764560 | c.1191T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764626 | c.1257C>T | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 764632 | c.1263T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764650 | c.1281G>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764695 | c.1326T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764752 | c.1383G>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764764 | c.1395T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764791 | c.1422C>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764809 | c.1440C>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R |
rpoC | 764812 | c.1443C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 764815 | c.1446A>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 764824 | c.1455T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764830 | c.1461C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 764858 | c.1489T>C | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 764893 | c.1524T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764911 | c.1542A>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764923 | c.1554A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
rpoC | 765349 | c.1980T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765352 | c.1983G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765383 | p.Met672Leu | missense_variant | 0.2 | rifampicin | Uncertain significance |
rpoC | 765404 | p.Leu679Val | missense_variant | 0.21 | rifampicin | |
rpoC | 765409 | c.2040T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765412 | c.2043T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765421 | c.2052C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765451 | c.2082C>G | synonymous_variant | 0.24 | rifampicin | |
rpoC | 765452 | c.2083_2085delGCCinsTG | frameshift_variant&missense_variant | 0.23 | rifampicin | |
rpoC | 765478 | c.2109T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765499 | c.2130C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765508 | c.2139C>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765535 | c.2166C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765541 | c.2172C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 765578 | c.2209C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765583 | c.2214G>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.2 | rifampicin | |
rpoC | 765625 | c.2256C>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765628 | c.2259G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 765631 | p.Asp754Glu | missense_variant | 0.19 | rifampicin | |
rpoC | 765658 | c.2289C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 765700 | c.2331T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765734 | c.2365T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765739 | c.2370G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765751 | c.2382C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765753 | p.Asp795Ala | missense_variant | 0.17 | rifampicin | Uncertain significance |
rpoC | 765772 | c.2403C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765784 | c.2415C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 765796 | c.2427C>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 765811 | c.2442T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765814 | c.2445A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765826 | c.2457T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 765883 | c.2514C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 765886 | c.2517C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 765892 | c.2523T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 765928 | c.2559C>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 765967 | c.2598C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765970 | c.2601C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 765979 | c.2610C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765982 | c.2613C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 765985 | c.2616C>T | synonymous_variant | 0.21 | rifampicin | |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoC | 766009 | c.2640G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 766010 | c.2641_2642delTCinsAG | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766021 | c.2652G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.2 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766069 | c.2700G>A | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766082 | p.Ala905Gln | missense_variant | 0.15 | rifampicin | |
rpoC | 766105 | c.2736C>T | synonymous_variant | 0.15 | rifampicin | |
rpoC | 766390 | c.3021C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766408 | c.3039C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 766426 | c.3057C>T | synonymous_variant | 0.23 | rifampicin | |
rpoC | 766447 | c.3078T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766483 | c.3114G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766484 | c.3115_3117delGTAinsAC | frameshift_variant&missense_variant | 0.17 | rifampicin | |
rpoC | 766492 | c.3123T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766495 | c.3126C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 766522 | c.3153C>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766528 | c.3159T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766531 | c.3162G>T | synonymous_variant | 0.19 | rifampicin | |
rpoC | 766543 | c.3174C>T | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766607 | c.3238_3240delATCinsCG | frameshift_variant&missense_variant | 0.16 | rifampicin | |
rpoC | 766630 | c.3261G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766645 | c.3276A>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766651 | c.3282T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766657 | c.3288A>G | synonymous_variant | 0.2 | rifampicin | |
rpoC | 766672 | c.3303T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 766738 | c.3369G>T | synonymous_variant | 0.26 | rifampicin | |
rpoC | 766750 | c.3381C>G | synonymous_variant | 0.27 | rifampicin | |
rpoC | 766765 | c.3396A>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766774 | c.3405T>C | synonymous_variant | 0.28 | rifampicin | |
rpoC | 766804 | c.3435A>G | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 766843 | c.3474T>C | synonymous_variant | 0.37 | rifampicin | Not assoc w R - Interim |
rpoC | 766861 | c.3492G>C | synonymous_variant | 0.35 | rifampicin | Not assoc w R - Interim |
rpoC | 766864 | c.3495G>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766895 | c.3526T>C | synonymous_variant | 0.35 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.36 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.33 | rifampicin | Not assoc w R - Interim |
rpoC | 766963 | c.3594T>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766972 | c.3603G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 766978 | c.3609C>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoC | 766996 | c.3627C>T | synonymous_variant | 0.32 | rifampicin | Not assoc w R - Interim |
rpoC | 767009 | c.3640_3642delTCGinsAGC | synonymous_variant | 0.3 | rifampicin | |
rpoC | 767014 | c.3645G>C | synonymous_variant | 0.31 | rifampicin | |
rpoC | 767033 | c.3664_3666delTCGinsAGC | synonymous_variant | 0.29 | rifampicin | |
rpoC | 767059 | c.3690T>G | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoC | 767062 | c.3693C>A | synonymous_variant | 0.22 | rifampicin | |
rpoC | 767074 | c.3705T>C | synonymous_variant | 0.23 | rifampicin | |
rpoC | 767098 | c.3729T>C | synonymous_variant | 0.25 | rifampicin | Not assoc w R - Interim |
rpoC | 767119 | c.3750A>G | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoC | 767134 | c.3765C>G | synonymous_variant | 0.21 | rifampicin | |
rpoC | 767158 | c.3789T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 775847 | c.2634G>C | synonymous_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775851 | p.Ser877Thr | missense_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775856 | c.2625T>C | synonymous_variant | 0.19 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775864 | p.Ala873Ser | missense_variant | 0.17 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775865 | c.2616T>G | synonymous_variant | 0.19 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775883 | c.2596_2598delATCinsTG | frameshift_variant&missense_variant | 0.19 | clofazimine | Uncertain significance |
bedaquiline | Uncertain significance | |||||
mmpL5 | 775886 | c.2595A>C | synonymous_variant | 0.21 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775898 | c.2583G>A | synonymous_variant | 0.23 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775901 | c.2580G>A | synonymous_variant | 0.19 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775904 | c.2577G>A | synonymous_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775909 | p.Leu858Phe | missense_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775912 | c.2569C>A | synonymous_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775916 | c.2565T>G | synonymous_variant | 0.25 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775937 | c.2544G>C | synonymous_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775966 | p.Ala839Ser | missense_variant | 0.26 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775975 | c.2506T>C | synonymous_variant | 0.21 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 775981 | p.Leu834Met | missense_variant | 0.18 | clofazimine | |
bedaquiline | ||||||
mmpL5 | 776009 | c.2472A>G | synonymous_variant | 0.17 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781631 | c.72G>C | synonymous_variant | 0.16 | streptomycin | |
rpsL | 781649 | c.90T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781655 | c.96T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781682 | c.123T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781715 | c.156T>C | synonymous_variant | 0.19 | streptomycin | |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.18 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781751 | c.192G>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781754 | c.195G>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781793 | c.234G>C | synonymous_variant | 0.17 | streptomycin | |
rpsL | 781832 | c.273T>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781841 | c.282C>G | synonymous_variant | 0.21 | streptomycin | |
rpsL | 781859 | c.300T>C | synonymous_variant | 0.21 | streptomycin | Not assoc w R - Interim |
rpsL | 781868 | c.309T>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781871 | c.312G>C | synonymous_variant | 0.2 | streptomycin | |
rpsL | 781892 | c.333A>G | synonymous_variant | 0.23 | streptomycin | |
rpsL | 781898 | c.339A>T | synonymous_variant | 0.24 | streptomycin | |
rpsL | 781916 | c.357T>C | synonymous_variant | 0.25 | streptomycin | |
rpsL | 781929 | p.Gly124Ser | missense_variant | 0.27 | streptomycin | Uncertain significance |
rplC | 800516 | c.-293G>T | upstream_gene_variant | 0.16 | linezolid | |
rplC | 800537 | c.-272C>T | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800540 | c.-269T>C | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800546 | c.-263T>C | upstream_gene_variant | 0.18 | linezolid | |
rplC | 800567 | c.-242A>G | upstream_gene_variant | 0.18 | linezolid | |
rplC | 800582 | c.-227C>G | upstream_gene_variant | 0.2 | linezolid | |
rplC | 800612 | c.-197A>G | upstream_gene_variant | 0.25 | linezolid | |
rplC | 800618 | c.-191T>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800648 | c.-161A>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800654 | c.-155T>C | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800690 | c.-119C>T | upstream_gene_variant | 0.24 | linezolid | |
rplC | 800693 | c.-116A>G | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800703 | c.-106T>C | upstream_gene_variant | 0.23 | linezolid | |
rplC | 800715 | c.-94A>C | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800720 | c.-89T>C | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800723 | c.-86C>G | upstream_gene_variant | 0.21 | linezolid | |
rplC | 800738 | c.-71T>C | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800747 | c.-62C>G | upstream_gene_variant | 0.17 | linezolid | |
rplC | 800771 | c.-38C>T | upstream_gene_variant | 0.19 | linezolid | |
rplC | 800814 | c.6A>G | synonymous_variant | 0.17 | linezolid | |
rplC | 800817 | c.9A>T | synonymous_variant | 0.18 | linezolid | |
rplC | 800844 | c.36T>C | synonymous_variant | 0.19 | linezolid | |
rplC | 800865 | c.57A>G | synonymous_variant | 0.17 | linezolid | |
rplC | 800867 | p.Ser20Asn | missense_variant | 0.17 | linezolid | |
rplC | 801174 | c.366T>C | synonymous_variant | 0.16 | linezolid | |
rplC | 801183 | c.375C>A | synonymous_variant | 0.16 | linezolid | |
rplC | 801222 | c.414T>C | synonymous_variant | 0.16 | linezolid | |
rplC | 801246 | c.438C>G | synonymous_variant | 0.17 | linezolid | |
rplC | 801249 | c.441T>G | synonymous_variant | 0.18 | linezolid | |
rplC | 801255 | c.447C>T | synonymous_variant | 0.19 | linezolid | |
rplC | 801267 | c.459A>C | synonymous_variant | 0.16 | linezolid | |
rplC | 801301 | c.493C>A | synonymous_variant | 0.14 | linezolid | |
fbiC | 1303575 | c.645G>C | synonymous_variant | 0.15 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303584 | c.654C>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303590 | c.660A>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303632 | c.702T>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303638 | c.708A>G | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303659 | c.729T>C | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303660 | p.Val244Thr | missense_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303674 | c.744C>G | synonymous_variant | 0.2 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303686 | c.756C>G | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303701 | c.771C>G | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303708 | c.778T>C | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303716 | c.786C>T | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303746 | c.816T>C | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303818 | c.888C>G | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303836 | c.906G>C | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303845 | c.915C>G | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303846 | p.Phe306Val | missense_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303854 | c.924T>C | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303860 | c.930A>C | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303881 | c.951G>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303884 | c.954T>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303911 | c.981G>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303914 | c.984C>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303920 | c.990C>G | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303923 | c.993C>T | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303929 | c.999G>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303947 | c.1017T>C | synonymous_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303948 | p.Gly340Arg | missense_variant | 0.21 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303973 | p.Gly348Ala | missense_variant | 0.24 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303981 | p.Val351Ile | missense_variant | 0.25 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1303995 | c.1065C>T | synonymous_variant | 0.24 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
fbiC | 1304001 | c.1071C>G | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304008 | c.1078T>C | synonymous_variant | 0.26 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304034 | c.1104A>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304040 | c.1110C>G | synonymous_variant | 0.15 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304046 | c.1116C>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304523 | c.1593G>T | synonymous_variant | 0.14 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304526 | c.1596T>A | synonymous_variant | 0.15 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304545 | p.Val539Ile | missense_variant | 0.15 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304559 | p.Glu543Asp | missense_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304727 | c.1797A>G | synonymous_variant | 0.15 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304742 | c.1812T>C | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304748 | c.1818T>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304754 | c.1824G>A | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304757 | c.1827A>G | synonymous_variant | 0.19 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304784 | c.1854T>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304787 | c.1857T>C | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304790 | c.1860C>G | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304856 | c.1926C>G | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304893 | p.Gly655Ser | missense_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304916 | c.1986T>C | synonymous_variant | 0.16 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1304961 | c.2031C>T | synonymous_variant | 0.15 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305331 | p.Glu801Lys | missense_variant | 0.14 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305381 | c.2451G>C | synonymous_variant | 0.18 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305393 | c.2463T>C | synonymous_variant | 0.17 | clofazimine | |
pretomanid | ||||||
delamanid | ||||||
fbiC | 1305405 | c.2475A>G | synonymous_variant | 0.16 | clofazimine | Not assoc w R - Interim |
pretomanid | ||||||
delamanid | ||||||
sigE | 1364802 | c.390C>A | synonymous_variant | 0.15 | pyrazinamide | |
sigE | 1364835 | c.423C>G | synonymous_variant | 0.16 | pyrazinamide | |
sigE | 1364839 | c.427T>C | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364862 | c.450C>G | synonymous_variant | 0.17 | pyrazinamide | |
sigE | 1364865 | c.453G>C | synonymous_variant | 0.18 | pyrazinamide | |
sigE | 1364866 | c.454_456delGCTinsTG | frameshift_variant&missense_variant | 0.17 | pyrazinamide | Uncertain significance |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1471923 | n.78T>C | non_coding_transcript_exon_variant | 0.16 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471934 | n.89A>G | non_coding_transcript_exon_variant | 0.19 | streptomycin | Uncertain significance |
kanamycin | ||||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471969 | n.124T>C | non_coding_transcript_exon_variant | 0.23 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1471970 | n.125G>A | non_coding_transcript_exon_variant | 0.21 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472028 | n.183A>T | non_coding_transcript_exon_variant | 0.21 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472030 | n.185G>A | non_coding_transcript_exon_variant | 0.21 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472031 | n.186G>A | non_coding_transcript_exon_variant | 0.21 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472034 | n.189T>C | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472044 | n.199G>C | non_coding_transcript_exon_variant | 0.27 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1472053 | n.211_212delGC | non_coding_transcript_exon_variant | 0.31 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472061 | n.216A>T | non_coding_transcript_exon_variant | 0.3 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472075 | n.230A>G | non_coding_transcript_exon_variant | 0.31 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 0.17 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 0.17 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 0.15 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 0.17 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473104 | n.1259C>T | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473105 | n.1260G>A | non_coding_transcript_exon_variant | 0.26 | streptomycin | |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473123 | n.1278delAinsTT | non_coding_transcript_exon_variant | 0.24 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrs | 1473145 | n.1300C>T | non_coding_transcript_exon_variant | 0.26 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrs | 1473166 | n.1321G>A | non_coding_transcript_exon_variant | 0.23 | streptomycin | Uncertain significance |
kanamycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
rrl | 1473756 | n.99G>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1473758 | n.101G>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473806 | n.149C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473813 | n.156C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1473839 | n.182G>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | |
linezolid | ||||||
rrl | 1473877 | n.220G>A | non_coding_transcript_exon_variant | 0.29 | capreomycin | |
linezolid | ||||||
rrl | 1473898 | n.241C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473899 | n.242A>C | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1473937 | n.280C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473944 | n.287G>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1473945 | n.288T>C | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1473981 | n.324delGinsTT | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.21 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1474051 | n.394T>C | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1474054 | n.397T>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474056 | n.399T>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474308 | n.651G>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474310 | n.653T>G | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1474356 | n.699T>C | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474362 | n.705A>G | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474812 | n.1155G>A | non_coding_transcript_exon_variant | 0.19 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1474831 | n.1174A>G | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | |
linezolid | ||||||
rrl | 1475088 | n.1431A>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475291 | n.1634A>C | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475313 | n.1656G>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1475315 | n.1658A>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475355 | n.1698C>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475369 | n.1712G>C | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475526 | n.1869C>A | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475659 | n.2002G>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | |
linezolid | ||||||
rrl | 1475763 | n.2106C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476045 | n.2388G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476047 | n.2390G>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | |
linezolid | ||||||
rrl | 1476049 | n.2392C>T | non_coding_transcript_exon_variant | 0.28 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 0.22 | capreomycin | |
linezolid | ||||||
rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 0.23 | capreomycin | |
linezolid | ||||||
rrl | 1476105 | n.2448_2449delGAinsT | non_coding_transcript_exon_variant | 0.24 | capreomycin | |
linezolid | ||||||
rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.23 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476628 | n.2971T>A | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476693 | n.3036G>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1476695 | n.3038T>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1476716 | n.3059A>C | non_coding_transcript_exon_variant | 0.2 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476723 | n.3066T>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1476725 | n.3068C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476726 | n.3069A>G | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
inhA | 1674279 | c.78A>C | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1674280 | p.Arg27Lys | missense_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674285 | c.84A>G | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674295 | p.Gln32Ala | missense_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674300 | c.99C>G | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1674303 | c.102C>G | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674307 | c.106C>T | synonymous_variant | 0.19 | ethionamide | |
isoniazid | ||||||
inhA | 1674315 | c.114C>G | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1674321 | c.120G>C | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674342 | c.141T>C | synonymous_variant | 0.22 | ethionamide | |
isoniazid | ||||||
inhA | 1674537 | c.336C>G | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674542 | p.Ala114Glu | missense_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674549 | c.348G>C | synonymous_variant | 0.17 | ethionamide | |
isoniazid | ||||||
inhA | 1674555 | c.354G>A | synonymous_variant | 0.17 | ethionamide | Not assoc w R - Interim |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674561 | c.360C>T | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1674564 | c.363C>T | synonymous_variant | 0.2 | ethionamide | |
isoniazid | Not assoc w R - Interim | |||||
inhA | 1674582 | c.381T>C | synonymous_variant | 0.2 | ethionamide | |
isoniazid | ||||||
inhA | 1674585 | c.384T>C | synonymous_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674589 | p.Met130Leu | missense_variant | 0.21 | ethionamide | |
isoniazid | ||||||
inhA | 1674636 | c.435C>G | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674639 | c.438C>T | synonymous_variant | 0.18 | ethionamide | |
isoniazid | ||||||
inhA | 1674654 | c.453G>C | synonymous_variant | 0.16 | ethionamide | |
isoniazid | ||||||
inhA | 1674994 | p.His265Asn | missense_variant | 0.15 | ethionamide | |
isoniazid | ||||||
rpsA | 1833568 | c.27G>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1833589 | c.48A>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833595 | c.54T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833619 | c.78A>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833661 | c.120A>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1833667 | c.126C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1833724 | c.183C>G | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1833727 | c.186G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1833742 | c.201A>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833745 | c.204G>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833787 | c.246C>G | synonymous_variant | 0.28 | pyrazinamide | |
rpsA | 1833790 | c.249T>A | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833799 | c.258C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833811 | c.270G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.29 | pyrazinamide | |
rpsA | 1833862 | c.321G>T | synonymous_variant | 0.3 | pyrazinamide | |
rpsA | 1833874 | c.333T>C | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1833970 | c.429G>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834015 | c.474G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834240 | c.699T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834249 | c.708T>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834261 | c.720A>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834264 | c.723G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834297 | c.756C>G | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834303 | c.762T>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834306 | c.765T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.26 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834375 | c.834G>A | synonymous_variant | 0.27 | pyrazinamide | |
rpsA | 1834396 | c.855G>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834411 | c.870T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834417 | c.876G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834423 | c.882G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834451 | c.910T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834474 | c.933C>G | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834498 | c.957C>T | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834555 | c.1014T>C | synonymous_variant | 0.25 | pyrazinamide | |
rpsA | 1834558 | c.1017C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834606 | c.1065C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834622 | c.1081_1083delTCGinsAGC | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1834666 | c.1125G>C | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834669 | c.1128G>C | synonymous_variant | 0.18 | pyrazinamide | |
rpsA | 1834688 | c.1147_1148delAGinsTC | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834836 | p.Met432Thr | missense_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
tsnR | 1853370 | c.-236G>T | upstream_gene_variant | 0.15 | linezolid | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
ndh | 2102009 | p.Ser345Asn | missense_variant | 0.17 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102020 | c.1023A>G | synonymous_variant | 0.17 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102023 | c.1020G>C | synonymous_variant | 0.17 | ethionamide | |
delamanid | ||||||
isoniazid | Not assoc w R - Interim | |||||
ndh | 2102026 | c.1017G>C | synonymous_variant | 0.18 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
ndh | 2102050 | c.993T>C | synonymous_variant | 0.16 | ethionamide | |
delamanid | ||||||
isoniazid | ||||||
katG | 2156196 | c.-85C>T | upstream_gene_variant | 1.0 | isoniazid | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
kasA | 2517947 | c.-168C>T | upstream_gene_variant | 0.27 | isoniazid | |
kasA | 2517974 | c.-141T>C | upstream_gene_variant | 0.18 | isoniazid | |
kasA | 2517989 | c.-126T>C | upstream_gene_variant | 0.18 | isoniazid | |
kasA | 2517992 | c.-123C>G | upstream_gene_variant | 0.17 | isoniazid | |
kasA | 2518480 | c.366T>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518483 | c.369C>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518504 | c.390T>C | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518506 | p.Ala131Glu | missense_variant | 0.2 | isoniazid | |
kasA | 2518519 | c.405G>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518528 | c.414C>G | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518540 | c.426T>G | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518561 | c.447T>C | synonymous_variant | 0.18 | isoniazid | |
kasA | 2518567 | c.453G>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518570 | c.456G>C | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518574 | c.460_462delATCinsGG | frameshift_variant&missense_variant | 0.18 | isoniazid | |
kasA | 2518588 | c.474T>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518591 | c.477G>C | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518609 | p.Met165Ile | missense_variant | 0.2 | isoniazid | |
kasA | 2518621 | c.507G>A | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518642 | c.528A>G | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518663 | c.549T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518672 | c.558G>C | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518687 | c.573C>T | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518690 | c.576C>T | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518696 | c.582C>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518702 | c.588C>T | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518711 | c.597A>G | synonymous_variant | 0.22 | isoniazid | |
kasA | 2518714 | c.600A>C | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518717 | c.603C>T | synonymous_variant | 0.25 | isoniazid | |
kasA | 2518732 | c.618C>G | synonymous_variant | 0.23 | isoniazid | |
kasA | 2518741 | c.627G>C | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518747 | c.633C>G | synonymous_variant | 0.24 | isoniazid | |
kasA | 2518768 | c.654C>G | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518783 | c.669T>C | synonymous_variant | 0.21 | isoniazid | |
kasA | 2518792 | c.678C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518795 | c.681C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518822 | c.708C>G | synonymous_variant | 0.19 | isoniazid | |
kasA | 2518825 | c.711T>C | synonymous_variant | 0.2 | isoniazid | |
kasA | 2518855 | c.741C>G | synonymous_variant | 0.17 | isoniazid | |
kasA | 2518919 | p.Gly269Ser | missense_variant | 0.92 | isoniazid | |
folC | 2746340 | p.Ala420Val | missense_variant | 1.0 | para-aminosalicylic_acid | |
folC | 2747355 | p.Val82Ile | missense_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2747359 | c.240C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
folC | 2747362 | c.237G>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
Rv2477c | 2782981 | c.1062G>C | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2782984 | c.1059T>C | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783002 | c.1041T>C | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783008 | c.1035C>G | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783013 | c.1030T>C | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783015 | p.Ser343Thr | missense_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783020 | c.1023G>C | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783040 | p.Ala335Thr | missense_variant | 0.28 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
amikacin | Uncertain significance | |||||
Rv2477c | 2783059 | c.984T>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783062 | c.981C>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783068 | p.Asp325Glu | missense_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783077 | c.966T>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783092 | c.951A>G | synonymous_variant | 0.24 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783095 | c.948C>G | synonymous_variant | 0.27 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783110 | c.933C>A | synonymous_variant | 0.3 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783140 | c.903C>G | synonymous_variant | 0.31 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783158 | c.885A>G | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783185 | c.858G>C | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783194 | c.849A>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783203 | c.840C>T | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783221 | c.822G>T | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783224 | c.819C>G | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783320 | c.723C>T | synonymous_variant | 0.15 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783365 | c.678C>T | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783373 | p.Glu224Gln | missense_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783395 | c.648T>C | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783440 | c.603T>C | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783461 | c.582T>C | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783467 | c.576G>C | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783512 | c.531A>G | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783520 | c.523T>C | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2783527 | c.516A>G | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783586 | p.Ala153Pro | missense_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783593 | c.450T>C | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783628 | p.Ala139Ser | missense_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783629 | c.414C>T | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783691 | c.352C>T | synonymous_variant | 0.16 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783751 | p.Ile98Val | missense_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783758 | p.Asp95Glu | missense_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783776 | c.267G>C | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783779 | c.264T>C | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783794 | c.249G>A | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783843 | p.Gly67Asp | missense_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783860 | p.Asp61Glu | missense_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783863 | c.180C>T | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783883 | c.160T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783884 | c.159T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783887 | c.156C>G | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783920 | c.123G>C | synonymous_variant | 0.33 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783953 | c.90G>A | synonymous_variant | 0.23 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783962 | c.81T>C | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | ||||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | Not assoc w R - Interim | |||||
Rv2477c | 2783971 | c.72G>C | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783980 | c.63C>G | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783992 | c.51T>C | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
amikacin | ||||||
Rv2477c | 2784405 | c.-363T>C | upstream_gene_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2752c | 3064962 | c.1230C>A | synonymous_variant | 0.14 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064973 | p.Ala407Ser | missense_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064974 | c.1218T>C | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064980 | c.1212C>A | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064995 | c.1197C>G | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3064998 | c.1194A>G | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065018 | p.Asn392His | missense_variant | 0.53 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065028 | c.1164G>C | synonymous_variant | 0.67 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065031 | c.1161G>C | synonymous_variant | 0.72 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065039 | c.1070_1152delNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNT | frameshift_variant | 1.0 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065040 | c.1152C>G | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065048 | c.1144C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065064 | c.1128G>C | synonymous_variant | 1.0 | ethambutol | Not assoc w R - Interim |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
Rv2752c | 3065979 | c.213T>C | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065993 | p.Val67Ile | missense_variant | 0.16 | ethambutol | Uncertain significance |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
Rv2752c | 3065994 | c.198T>C | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3065997 | c.195C>G | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066002 | p.Met64Leu | missense_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066024 | c.168T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066040 | p.Gly51Thr | missense_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066042 | c.150T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066050 | p.Leu48Met | missense_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066054 | c.138T>G | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066066 | c.126T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066075 | c.117A>G | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
Rv2752c | 3066087 | c.105A>G | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
thyX | 3067391 | c.555G>C | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyX | 3067394 | c.552G>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067412 | c.534C>G | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyX | 3067439 | c.507A>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067470 | p.Asn159Ser | missense_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067500 | p.Lys149Arg | missense_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.24 | para-aminosalicylic_acid | |
thyX | 3067526 | c.420C>G | synonymous_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.27 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.22 | para-aminosalicylic_acid | |
thyX | 3067556 | p.His130Gln | missense_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067559 | p.Arg129Gln | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067565 | p.Asp127Glu | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067570 | p.Ala126Pro | missense_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067571 | c.375C>T | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067577 | p.Glu123Asp | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067582 | p.Met122Leu | missense_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067586 | c.360C>G | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067601 | c.345G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067604 | c.342G>C | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067613 | c.333G>A | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067619 | c.327A>C | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyX | 3067640 | c.306G>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067643 | c.303C>T | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067652 | c.294T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067661 | c.285C>G | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
thyX | 3067718 | c.228C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067721 | c.225T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyX | 3067724 | c.222G>A | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067727 | c.219A>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067739 | c.207T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyX | 3067742 | c.204A>C | synonymous_variant | 0.18 | para-aminosalicylic_acid | |
thyX | 3067762 | c.184C>A | synonymous_variant | 0.14 | para-aminosalicylic_acid | |
thyX | 3067765 | p.Leu61Ile | missense_variant | 0.14 | para-aminosalicylic_acid | |
thyX | 3067787 | c.159G>A | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyX | 3067826 | c.120C>G | synonymous_variant | 0.15 | para-aminosalicylic_acid | |
thyA | 3073863 | c.609T>C | synonymous_variant | 0.16 | para-aminosalicylic_acid | |
thyA | 3073868 | p.Thr202Ala | missense_variant | 0.83 | para-aminosalicylic_acid | |
thyA | 3073872 | c.598_600delATCinsGG | frameshift_variant&missense_variant | 0.17 | para-aminosalicylic_acid | |
thyA | 3073878 | c.594G>A | synonymous_variant | 0.19 | para-aminosalicylic_acid | |
thyA | 3073892 | c.580T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3073893 | c.579C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3073925 | c.547T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3073926 | c.546G>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3073929 | c.543T>C | synonymous_variant | 0.21 | para-aminosalicylic_acid | |
thyA | 3073953 | c.519T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3073977 | c.495A>G | synonymous_variant | 0.22 | para-aminosalicylic_acid | |
thyA | 3073989 | c.483T>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074001 | c.471C>G | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3074004 | c.468T>C | synonymous_variant | 0.25 | para-aminosalicylic_acid | |
thyA | 3074010 | c.462C>A | synonymous_variant | 0.28 | para-aminosalicylic_acid | |
thyA | 3074031 | c.441T>C | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074037 | c.435C>G | synonymous_variant | 0.27 | para-aminosalicylic_acid | |
thyA | 3074056 | p.Glu139Pro | missense_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074061 | c.411A>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074076 | c.396C>G | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074082 | c.390G>C | synonymous_variant | 0.23 | para-aminosalicylic_acid | |
thyA | 3074097 | c.375C>G | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3074100 | c.372T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3074106 | c.366T>C | synonymous_variant | 0.2 | para-aminosalicylic_acid | |
thyA | 3074117 | c.355C>T | synonymous_variant | 0.17 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
lpqB | 3624401 | c.510C>T | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624464 | c.447A>G | synonymous_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624470 | c.441T>C | synonymous_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624476 | c.435C>G | synonymous_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624482 | c.429T>C | synonymous_variant | 0.16 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3624485 | p.Asp142Gly | missense_variant | 0.17 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
lpqB | 3624512 | c.399C>G | synonymous_variant | 0.15 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624713 | c.198C>T | synonymous_variant | 0.15 | bedaquiline | |
rifampicin | ||||||
lpqB | 3624728 | c.183C>T | synonymous_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrB | 3625572 | p.Thr348Ser | missense_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625579 | c.-669A>G | upstream_gene_variant | 0.18 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625592 | p.Ser341Asn | missense_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625594 | c.-684T>C | upstream_gene_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625602 | c.-692T>C | upstream_gene_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625612 | c.-702G>C | upstream_gene_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625616 | p.Arg333Ala | missense_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625624 | c.-714C>G | upstream_gene_variant | 0.26 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625627 | c.-717C>T | upstream_gene_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625648 | c.-738T>C | upstream_gene_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625656 | c.958T>C | synonymous_variant | 0.28 | bedaquiline | Not assoc w R - Interim |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625663 | c.-753G>C | upstream_gene_variant | 0.29 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625669 | c.-759G>C | upstream_gene_variant | 0.28 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625690 | c.-780T>C | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
lpqB | 3625696 | c.-786A>G | upstream_gene_variant | 0.22 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625705 | c.909C>G | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625714 | c.-804C>T | upstream_gene_variant | 0.25 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625720 | c.894G>C | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625729 | c.885A>G | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625735 | c.879C>A | synonymous_variant | 0.27 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625750 | c.864G>A | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.25 | bedaquiline | |
rifampicin | Uncertain significance | |||||
mtrB | 3625762 | c.852A>G | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625765 | c.849C>G | synonymous_variant | 0.25 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625797 | p.Val273Met | missense_variant | 0.28 | bedaquiline | Uncertain significance |
rifampicin | Uncertain significance | |||||
mtrB | 3625806 | c.808A>C | synonymous_variant | 0.26 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3625837 | c.777C>G | synonymous_variant | 0.19 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625840 | c.-930A>G | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625852 | c.762A>G | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
lpqB | 3625864 | c.-954T>G | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626723 | c.627C>T | synonymous_variant | 0.14 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626759 | c.591T>C | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3626774 | c.574_576delAGGinsCC | frameshift_variant&missense_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626780 | c.-167T>C | upstream_gene_variant | 0.18 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626783 | c.-170C>G | upstream_gene_variant | 0.2 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626786 | c.564A>G | synonymous_variant | 0.21 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626795 | c.-182C>T | upstream_gene_variant | 0.21 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626798 | c.-185T>C | upstream_gene_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626804 | c.546A>G | synonymous_variant | 0.21 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626840 | c.-227C>G | upstream_gene_variant | 0.21 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626846 | c.504G>A | synonymous_variant | 0.2 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626858 | c.-245A>G | upstream_gene_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626861 | c.-248C>G | upstream_gene_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626866 | c.-253T>C | upstream_gene_variant | 0.19 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626885 | c.-272A>C | upstream_gene_variant | 0.2 | bedaquiline | |
rifampicin | ||||||
mtrB | 3626903 | c.-290T>C | upstream_gene_variant | 0.18 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626912 | c.438T>C | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626930 | c.-317A>T | upstream_gene_variant | 0.21 | bedaquiline | |
rifampicin | ||||||
mtrA | 3626939 | c.411A>G | synonymous_variant | 0.24 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3626942 | c.-329A>G | upstream_gene_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627008 | c.-395G>C | upstream_gene_variant | 0.23 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627011 | c.-398T>G | upstream_gene_variant | 0.24 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627065 | c.-452G>C | upstream_gene_variant | 0.2 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627068 | c.282T>C | synonymous_variant | 0.2 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627074 | c.-461G>C | upstream_gene_variant | 0.2 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627080 | c.270T>C | synonymous_variant | 0.16 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627104 | c.-491C>G | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627119 | c.231T>G | synonymous_variant | 0.18 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627122 | c.-509T>C | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627128 | c.-515T>C | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627139 | c.-526T>C | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627215 | c.135G>A | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.17 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.17 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.16 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
rpoA | 3877542 | c.966C>T | synonymous_variant | 0.16 | rifampicin | |
rpoA | 3877553 | p.Glu319Gln | missense_variant | 0.16 | rifampicin | |
rpoA | 3877557 | c.951C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3877587 | c.921A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877613 | p.Ile299Val | missense_variant | 0.23 | rifampicin | |
rpoA | 3877638 | c.870T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877656 | c.852T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877668 | c.840A>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3877677 | p.Ala277Ser | missense_variant | 0.17 | rifampicin | |
rpoA | 3877680 | c.828G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3877686 | c.822A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3877692 | c.816G>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3877704 | c.804G>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.27 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3877782 | c.726T>C | synonymous_variant | 0.26 | rifampicin | Not assoc w R - Interim |
rpoA | 3877818 | c.690A>G | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3877839 | c.669G>C | synonymous_variant | 0.29 | rifampicin | Not assoc w R - Interim |
rpoA | 3877857 | c.651G>A | synonymous_variant | 0.31 | rifampicin | |
rpoA | 3877866 | c.642G>C | synonymous_variant | 0.3 | rifampicin | |
rpoA | 3877872 | c.636C>T | synonymous_variant | 0.31 | rifampicin | Not assoc w R - Interim |
rpoA | 3877875 | c.633T>G | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3877899 | p.Ser203Thr | missense_variant | 0.22 | rifampicin | |
rpoA | 3877905 | c.603A>G | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3877908 | p.Asn200Ser | missense_variant | 0.21 | rifampicin | |
rpoA | 3877953 | c.555G>A | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3877962 | c.546G>T | synonymous_variant | 0.23 | rifampicin | Not assoc w R - Interim |
rpoA | 3877986 | c.522G>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3877989 | c.519A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3878001 | c.507A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3878022 | c.486T>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878025 | c.483C>T | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878028 | c.480G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878031 | c.477T>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878040 | c.468T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3878046 | c.462T>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878049 | c.459G>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878055 | c.453A>G | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878061 | c.447G>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878067 | c.441C>G | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878070 | c.438T>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878082 | c.426T>C | synonymous_variant | 0.2 | rifampicin | |
rpoA | 3878094 | c.414C>G | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878100 | c.408C>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878103 | c.405A>G | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878106 | c.402G>C | synonymous_variant | 0.23 | rifampicin | |
rpoA | 3878118 | c.390T>C | synonymous_variant | 0.26 | rifampicin | |
rpoA | 3878141 | p.Met123Leu | missense_variant | 0.23 | rifampicin | Uncertain significance |
rpoA | 3878142 | p.Gly122Glu | missense_variant | 0.23 | rifampicin | |
rpoA | 3878169 | c.339G>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoA | 3878184 | c.324C>T | synonymous_variant | 0.24 | rifampicin | Not assoc w R - Interim |
rpoA | 3878187 | c.321C>G | synonymous_variant | 0.24 | rifampicin | |
rpoA | 3878193 | c.315T>C | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3878199 | c.309T>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878202 | c.306G>C | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878217 | c.291A>G | synonymous_variant | 0.22 | rifampicin | Not assoc w R - Interim |
rpoA | 3878220 | c.288C>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3878271 | c.237T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoA | 3878284 | p.Glu75Ala | missense_variant | 0.19 | rifampicin | |
rpoA | 3878292 | c.216T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3878298 | c.210A>G | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878304 | c.204G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878313 | c.195G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoA | 3878322 | c.186A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoA | 3878334 | c.174T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3878337 | c.171T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoA | 3878346 | c.162T>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878364 | c.144A>G | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878367 | c.141C>G | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878370 | c.138T>C | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878376 | c.132G>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878385 | c.123C>G | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878391 | c.117T>C | synonymous_variant | 0.22 | rifampicin | |
rpoA | 3878396 | c.112C>T | synonymous_variant | 0.21 | rifampicin | |
rpoA | 3878436 | c.72A>G | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878442 | c.66G>C | synonymous_variant | 0.18 | rifampicin | |
rpoA | 3878454 | c.54A>C | synonymous_variant | 0.17 | rifampicin | |
rpoA | 3878490 | c.18C>A | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3878496 | c.12A>T | synonymous_variant | 0.19 | rifampicin | |
rpoA | 3878742 | c.-235G>A | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878781 | c.-274A>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878782 | c.-275G>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878785 | c.-278T>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878788 | c.-281G>C | upstream_gene_variant | 0.16 | rifampicin | Uncertain significance |
rpoA | 3878806 | c.-299C>A | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878809 | c.-302T>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3878853 | c.-346G>A | upstream_gene_variant | 0.15 | rifampicin | |
rpoA | 3878989 | c.-482G>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3879037 | c.-530G>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879040 | c.-533G>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879079 | c.-572A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879088 | c.-581A>C | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879094 | c.-587T>C | upstream_gene_variant | 0.19 | rifampicin | |
rpoA | 3879121 | c.-614T>G | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879127 | c.-620T>C | upstream_gene_variant | 0.23 | rifampicin | |
rpoA | 3879136 | c.-629A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879154 | c.-647T>C | upstream_gene_variant | 0.22 | rifampicin | |
rpoA | 3879160 | c.-653A>G | upstream_gene_variant | 0.21 | rifampicin | |
rpoA | 3879178 | c.-671T>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoA | 3879190 | c.-683C>G | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3879222 | c.-715T>C | upstream_gene_variant | 0.16 | rifampicin | |
rpoA | 3879226 | c.-719G>C | upstream_gene_variant | 0.16 | rifampicin | |
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 0.85 | pyrazinamide | Not assoc w R |
clpC1 | 4038293 | c.2412G>C | synonymous_variant | 0.15 | pyrazinamide | |
clpC1 | 4038302 | c.2403C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4038308 | c.2395_2397delGTGinsAC | frameshift_variant&missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4038317 | c.2388G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038347 | c.2358G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038356 | c.2349T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038368 | c.2337T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038444 | p.Ala754Lys | missense_variant | 0.16 | pyrazinamide | |
clpC1 | 4038446 | c.2259T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4038461 | p.Ala748Asp | missense_variant | 0.17 | pyrazinamide | |
clpC1 | 4038498 | p.Ser736Thr | missense_variant | 0.2 | pyrazinamide | |
clpC1 | 4038530 | p.Glu725Asp | missense_variant | 0.23 | pyrazinamide | |
clpC1 | 4038536 | c.2169C>T | synonymous_variant | 0.23 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038596 | c.2109A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038640 | p.Asp689Asn | missense_variant | 0.15 | pyrazinamide | |
clpC1 | 4038683 | c.2022T>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038695 | c.2010C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038701 | c.2004G>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038704 | c.2001T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038707 | c.1998C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038710 | c.1995G>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038713 | c.1992T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038740 | c.1965G>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038755 | c.1950G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038773 | c.1932T>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038782 | c.1923G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4038790 | c.1915C>T | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038812 | c.1893T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038815 | c.1890G>T | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4038851 | c.1854G>A | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038878 | c.1827A>G | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038908 | c.1797C>G | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038914 | c.1791G>C | synonymous_variant | 0.24 | pyrazinamide | |
clpC1 | 4038923 | c.1782A>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038932 | c.1773G>C | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4038953 | c.1752A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038956 | c.1749T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038965 | c.1740T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038971 | c.1734T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4038974 | c.1731T>C | synonymous_variant | 0.2 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4038989 | c.1716T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4038997 | c.1708T>C | synonymous_variant | 0.19 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039022 | c.1683A>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039073 | c.1632C>G | synonymous_variant | 0.22 | pyrazinamide | |
clpC1 | 4039085 | c.1620A>G | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039090 | c.1615C>T | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039097 | c.1608G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039103 | c.1602T>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039106 | c.1599G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039112 | c.1593C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039121 | c.1584T>C | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039124 | c.1581C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039127 | c.1578G>A | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039145 | c.1560G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4039469 | c.1236T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039481 | c.1224T>G | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039484 | c.1221T>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039493 | c.1212C>T | synonymous_variant | 0.21 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039517 | c.1188C>G | synonymous_variant | 0.25 | pyrazinamide | |
clpC1 | 4039524 | p.Phe394Tyr | missense_variant | 0.21 | pyrazinamide | |
clpC1 | 4039526 | c.1179G>C | synonymous_variant | 0.21 | pyrazinamide | |
clpC1 | 4039532 | c.1173C>T | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039547 | c.1158C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039553 | c.1152C>G | synonymous_variant | 0.23 | pyrazinamide | |
clpC1 | 4039562 | c.1143C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039576 | p.Ala377Ser | missense_variant | 0.25 | pyrazinamide | |
clpC1 | 4039577 | c.1128T>C | synonymous_variant | 0.25 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4039586 | c.1119G>C | synonymous_variant | 0.27 | pyrazinamide | |
clpC1 | 4039610 | c.1095G>C | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039616 | c.1089G>C | synonymous_variant | 0.28 | pyrazinamide | |
clpC1 | 4039622 | c.1083C>G | synonymous_variant | 0.26 | pyrazinamide | |
clpC1 | 4039682 | c.1023C>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039685 | c.1020C>T | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039850 | c.855T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039865 | c.840T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039898 | c.807C>G | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4039904 | c.801A>G | synonymous_variant | 0.2 | pyrazinamide | |
clpC1 | 4039928 | c.775_777delAGCinsTCG | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039931 | c.774T>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4039946 | c.759A>T | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039952 | c.753T>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4039958 | c.747G>C | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040021 | c.684A>C | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040354 | c.351A>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040363 | c.342A>C | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040369 | c.336C>G | synonymous_variant | 0.18 | pyrazinamide | |
clpC1 | 4040380 | c.325T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040387 | c.318A>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040393 | c.312G>C | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040411 | c.294T>C | synonymous_variant | 0.16 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040431 | c.274T>C | synonymous_variant | 0.19 | pyrazinamide | |
clpC1 | 4040444 | c.261C>G | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040528 | c.177G>C | synonymous_variant | 0.16 | pyrazinamide | |
glpK | 4138502 | c.1254T>G | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138511 | c.1245C>T | synonymous_variant | 0.16 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138514 | c.1242A>G | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138518 | p.Glu413Ala | missense_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138523 | c.1233C>G | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138535 | c.1221T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138538 | c.1218C>T | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138547 | c.1209C>T | synonymous_variant | 0.22 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | Not assoc w R - Interim | |||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138568 | c.1188A>G | synonymous_variant | 0.28 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138571 | c.1185C>G | synonymous_variant | 0.29 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138583 | c.1173G>C | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138586 | c.1170C>T | synonymous_variant | 0.27 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138606 | c.1150T>C | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138631 | c.1125C>G | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138634 | c.1122G>T | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138643 | c.1113A>C | synonymous_variant | 0.26 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138664 | c.1092G>C | synonymous_variant | 0.21 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138667 | c.1089G>C | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.22 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138679 | c.1075_1077delATGinsGC | frameshift_variant&missense_variant | 0.22 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138703 | c.1053C>G | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138706 | c.1050C>G | synonymous_variant | 0.18 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138714 | p.Ala348Ser | missense_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138715 | c.1041G>A | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139165 | c.591A>G | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139168 | c.588T>C | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139175 | p.Val194Ala | missense_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139540 | p.Ile72Met | missense_variant | 0.14 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139552 | c.202_204delGCGinsTC | frameshift_variant&missense_variant | 0.18 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4139575 | p.Val61Ile | missense_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139581 | p.Asn59Asp | missense_variant | 0.22 | ethambutol | Uncertain significance |
moxifloxacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
levofloxacin | Uncertain significance | |||||
rifampicin | Uncertain significance | |||||
isoniazid | Uncertain significance | |||||
glpK | 4139588 | c.168G>C | synonymous_variant | 0.24 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139597 | c.159C>G | synonymous_variant | 0.25 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139630 | c.126C>T | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4139651 | p.His35Gln | missense_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
embC | 4240632 | p.Met257Thr | missense_variant | 0.18 | ethambutol | |
embC | 4240642 | c.780G>C | synonymous_variant | 0.18 | ethambutol | |
embC | 4240645 | c.783G>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4240671 | p.Thr270Ile | missense_variant | 0.17 | ethambutol | Not assoc w R |
embC | 4240706 | p.Val282Met | missense_variant | 0.14 | ethambutol | |
embC | 4240726 | c.864G>C | synonymous_variant | 0.18 | ethambutol | Not assoc w R - Interim |
embC | 4240783 | c.921G>C | synonymous_variant | 0.28 | ethambutol | |
embC | 4240789 | c.927T>C | synonymous_variant | 0.24 | ethambutol | |
embC | 4240819 | c.957A>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4240831 | c.969T>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4240867 | c.1005T>G | synonymous_variant | 0.16 | ethambutol | |
embC | 4240945 | c.1083T>C | synonymous_variant | 0.15 | ethambutol | |
embC | 4240966 | c.1104G>T | synonymous_variant | 0.17 | ethambutol | Not assoc w R - Interim |
embC | 4240980 | p.Thr373Lys | missense_variant | 0.15 | ethambutol | |
embC | 4240990 | c.1128A>G | synonymous_variant | 0.17 | ethambutol | |
embC | 4240996 | c.1134G>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4241017 | c.1155T>C | synonymous_variant | 0.21 | ethambutol | |
embC | 4241023 | c.1161T>G | synonymous_variant | 0.22 | ethambutol | |
embC | 4241026 | c.1164C>G | synonymous_variant | 0.23 | ethambutol | |
embC | 4241035 | c.1173G>A | synonymous_variant | 0.22 | ethambutol | |
embC | 4241050 | c.1188T>G | synonymous_variant | 0.22 | ethambutol | |
embC | 4241086 | c.1224G>C | synonymous_variant | 0.19 | ethambutol | |
embC | 4241104 | c.1242G>A | synonymous_variant | 0.16 | ethambutol | Not assoc w R - Interim |
embC | 4241107 | c.1245G>C | synonymous_variant | 0.17 | ethambutol | |
embC | 4241141 | p.Ile427Val | missense_variant | 0.16 | ethambutol | Uncertain significance |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4245089 | c.1857G>C | synonymous_variant | 0.17 | ethambutol | |
embA | 4245092 | c.1860C>G | synonymous_variant | 0.16 | ethambutol | |
embA | 4245137 | c.1905T>C | synonymous_variant | 0.19 | ethambutol | |
embA | 4245149 | c.1917C>G | synonymous_variant | 0.19 | ethambutol | |
embA | 4245182 | c.1950T>C | synonymous_variant | 0.18 | ethambutol | |
embA | 4245194 | c.1962G>C | synonymous_variant | 0.16 | ethambutol | |
embA | 4245198 | p.Leu656Ile | missense_variant | 0.16 | ethambutol | |
embB | 4247389 | c.876C>G | synonymous_variant | 0.15 | ethambutol | |
embB | 4247395 | c.882C>G | synonymous_variant | 0.16 | ethambutol | |
embB | 4247401 | c.888T>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4247437 | c.924A>G | synonymous_variant | 0.2 | ethambutol | Not assoc w R - Interim |
embB | 4247440 | c.927C>G | synonymous_variant | 0.2 | ethambutol | |
embB | 4247464 | c.951C>G | synonymous_variant | 0.18 | ethambutol | |
embB | 4247470 | c.957T>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4247491 | c.978G>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4247497 | c.984T>C | synonymous_variant | 0.16 | ethambutol | |
embB | 4248035 | p.Val508Ile | missense_variant | 0.14 | ethambutol | |
embB | 4248041 | p.Ala510Thr | missense_variant | 0.15 | ethambutol | Uncertain significance |
embB | 4248055 | c.1542G>A | synonymous_variant | 0.14 | ethambutol | Not assoc w R - Interim |
embB | 4248085 | c.1572T>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4248097 | c.1584C>G | synonymous_variant | 0.18 | ethambutol | |
embB | 4248157 | c.1644A>G | synonymous_variant | 0.15 | ethambutol | Not assoc w R - Interim |
embB | 4248206 | c.1693_1695delAGCinsGG | frameshift_variant&missense_variant | 0.21 | ethambutol | |
embB | 4248220 | c.1707A>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
embB | 4248241 | c.1728C>T | synonymous_variant | 0.2 | ethambutol | |
embB | 4248265 | c.1752C>T | synonymous_variant | 0.22 | ethambutol | |
embB | 4248266 | c.1753C>T | synonymous_variant | 0.22 | ethambutol | |
embB | 4248277 | c.1764G>C | synonymous_variant | 0.23 | ethambutol | |
embB | 4249498 | c.2985G>C | synonymous_variant | 0.17 | ethambutol | |
embB | 4249521 | p.Ala1003Val | missense_variant | 0.15 | ethambutol | |
embB | 4249532 | p.Ala1007Thr | missense_variant | 0.15 | ethambutol | Uncertain significance |
ubiA | 4269149 | p.Val229Leu | missense_variant | 0.16 | ethambutol | Uncertain significance |
aftB | 4269183 | c.-347T>C | upstream_gene_variant | 0.18 | ethambutol | |
aftB | 4269201 | c.-365A>G | upstream_gene_variant | 0.21 | ethambutol | |
ubiA | 4269209 | p.Ser209Ala | missense_variant | 0.21 | ethambutol | |
ubiA | 4269220 | p.Ala205Lys | missense_variant | 0.2 | ethambutol | |
ubiA | 4269222 | c.612T>G | synonymous_variant | 0.21 | ethambutol | Not assoc w R - Interim |
aftB | 4269225 | c.-389C>G | upstream_gene_variant | 0.2 | ethambutol | |
aftB | 4269231 | c.-395C>G | upstream_gene_variant | 0.21 | ethambutol | |
aftB | 4269234 | c.-398A>G | upstream_gene_variant | 0.22 | ethambutol | |
ubiA | 4269243 | p.His197Gln | missense_variant | 0.21 | ethambutol | |
ubiA | 4269271 | p.Val188Ala | missense_variant | 0.16 | ethambutol | Uncertain significance |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
gid | 4408156 | p.Leu16Arg | missense_variant | 1.0 | streptomycin | Not assoc w R |