TB-Profiler result

Run: ERR5979654
Summary

Run ID: ERR5979654

Sample name:

Date: 02-04-2023 01:17:54

Number of reads: 4758099

Percentage reads mapped: 99.8

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
mmpR5 779181 c.198dupG frameshift_variant 1.0 clofazimine, bedaquiline
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.27
mshA 576482 p.Val379Leu missense_variant 0.16
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.19
fbiD 3339734 p.Ala206Gly missense_variant 0.37
rpoA 3878637 c.-130G>C upstream_gene_variant 0.22
rpoA 3878641 c.-134C>G upstream_gene_variant 0.18
embB 4246584 p.Arg24Pro missense_variant 0.43