TB-Profiler result

Run: ERR5979744
Summary

Run ID: ERR5979744

Sample name:

Date: 02-04-2023 01:21:39

Number of reads: 2583517

Percentage reads mapped: 99.94

Strain: lineage4.9

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
mmpR5 779181 c.198dupG frameshift_variant 1.0 clofazimine, bedaquiline
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
mshA 576108 p.Ala254Gly missense_variant 0.18
mshA 576482 p.Val379Leu missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.2
fbiD 3339734 p.Ala206Gly missense_variant 0.6
fbiD 3339746 p.Ala210Gly missense_variant 0.23
rpoA 3878641 c.-134C>G upstream_gene_variant 0.32
embB 4246584 p.Arg24Pro missense_variant 0.46