TB-Profiler result

Run: ERR5979795
Summary

Run ID: ERR5979795

Sample name:

Date: 02-04-2023 01:23:41

Number of reads: 920712

Percentage reads mapped: 97.79

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7728 c.430delG frameshift_variant 0.13
gyrA 8895 p.Asp532Asn missense_variant 0.12
mshA 576356 p.Ala337Thr missense_variant 0.11
rpoB 762147 p.Arg781Trp missense_variant 0.15
rpoC 763789 p.Asp140Glu missense_variant 0.15
rpoC 765934 c.2565C>T synonymous_variant 0.18
mmpR5 778198 c.-792G>A upstream_gene_variant 0.2
mmpR5 779181 c.198delG frameshift_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
ndh 2102367 p.Ala226Pro missense_variant 0.15
ndh 2102368 c.675C>T synonymous_variant 0.15
ndh 2102377 c.666A>G synonymous_variant 0.14
kasA 2518993 c.879C>A synonymous_variant 0.11
kasA 2519227 c.1113G>A synonymous_variant 0.14
pepQ 2860159 p.Ala87Gly missense_variant 0.19
fbiD 3339734 p.Ala206Gly missense_variant 0.38
Rv3236c 3612273 p.Val282Ile missense_variant 0.11
Rv3236c 3613049 p.Ala23Val missense_variant 0.13
embC 4240420 c.558T>G synonymous_variant 0.21
embB 4246584 p.Arg24Pro missense_variant 0.44
embB 4248319 c.1806A>T synonymous_variant 0.21