TB-Profiler result

Run: ERR751989
Summary

Run ID: ERR751989

Sample name:

Date: 02-04-2023 04:52:09

Number of reads: 983610

Percentage reads mapped: 99.08

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5195 c.-45C>A upstream_gene_variant 0.14
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9788 p.Asp829Glu missense_variant 1.0
fgd1 490751 c.-32T>G upstream_gene_variant 0.21
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoB 760633 p.Arg276His missense_variant 0.17
rpoC 763190 c.-180C>T upstream_gene_variant 0.13
rpoC 767157 p.Gly1263Asp missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777266 c.1215G>T synonymous_variant 0.22
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302976 p.Val16Ile missense_variant 0.12
fbiC 1303904 p.Leu325Pro missense_variant 0.12
Rv1258c 1406570 c.771G>A synonymous_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rpsA 1833970 c.429G>A synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155171 p.Thr314Ile missense_variant 0.17
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2221722 c.1443C>T synonymous_variant 1.0
Rv1979c 2223086 c.77_78delCG frameshift_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288815 p.Ala143Ser missense_variant 0.14
pncA 2289790 c.-549C>T upstream_gene_variant 0.13
pepQ 2860171 p.Leu83Pro missense_variant 0.13
thyA 3074319 p.His51Gln missense_variant 0.13
fbiD 3339060 c.-58C>A upstream_gene_variant 0.12
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641555 c.21C>T synonymous_variant 0.83
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 0.98
embC 4242035 p.Gln725Lys missense_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249132 c.2619G>A synonymous_variant 0.17
whiB6 4338286 c.235delG frameshift_variant 0.92
whiB6 4338595 c.-75delG upstream_gene_variant 1.0