TB-Profiler result

Run: ERR7764395
Summary

Run ID: ERR7764395

Sample name:

Date: 02-04-2023 05:46:09

Number of reads: 1263825

Percentage reads mapped: 99.29

Strain: lineage4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7786 p.Glu162Ala missense_variant 0.19
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9649 p.Val783Gly missense_variant 0.31
mshA 576108 p.Ala254Gly missense_variant 0.33
mshA 576446 p.Thr367Pro missense_variant 0.2
mshA 576618 p.His424Pro missense_variant 0.29
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154733 p.Ser460Asn missense_variant 1.0
PPE35 2170048 p.Leu189Val missense_variant 0.53
PPE35 2170053 p.Thr187Ser missense_variant 0.64
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289787 c.-546A>C upstream_gene_variant 0.25
ahpC 2726210 c.18T>C synonymous_variant 1.0
pepQ 2859931 p.Leu163Gln missense_variant 0.17
ribD 2987506 p.Leu223Gln missense_variant 0.17
thyX 3067944 p.Val1Gly missense_variant 0.21
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339698 p.Asp194Ala missense_variant 0.38
fbiD 3339751 p.Ala212Pro missense_variant 0.29
Rv3083 3449926 p.Glu475Lys missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568428 c.252A>C synonymous_variant 0.33
fbiA 3641447 p.Thr302Met missense_variant 1.0
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.25
embC 4240427 p.Ser189Cys missense_variant 0.27
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embA 4243682 c.450T>G synonymous_variant 0.23
embB 4246527 p.Ala5Gly missense_variant 0.18
embB 4248324 p.Ala604Gly missense_variant 0.11
embB 4248328 c.1815G>C synonymous_variant 0.22
embB 4249408 c.2895G>A synonymous_variant 1.0
embB 4249730 c.3219_3221delCCC disruptive_inframe_deletion 0.17
ethA 4328025 c.-552T>G upstream_gene_variant 0.26
whiB6 4338200 p.Asp108His missense_variant 0.17
whiB6 4338498 p.Glu8Asp missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407868 p.Val112Gly missense_variant 1.0