TB-Profiler result

Run: ERR8975158
Summary

Run ID: ERR8975158

Sample name:

Date: 02-04-2023 08:42:32

Number of reads: 3127661

Percentage reads mapped: 99.59

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9138 p.Gln613Glu missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576304 c.957G>A synonymous_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777416 c.1065G>T synonymous_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304404 p.Asp492Asn missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2168479 p.Thr712Pro missense_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518887 p.Gly258Asp missense_variant 0.12
kasA 2518977 p.Gly288Asp missense_variant 0.17
folC 2746470 p.Gly377Arg missense_variant 0.25
folC 2746632 p.Gly323Ser missense_variant 0.5
folC 2746683 p.Leu306Phe missense_variant 0.22
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568779 c.-100T>C upstream_gene_variant 0.99
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
fbiA 3640812 p.Gln90His missense_variant 1.0
embA 4243515 p.Ala95Ser missense_variant 0.67
embA 4243542 p.Gly104Trp missense_variant 0.67
embA 4243563 p.Gln111* stop_gained 1.0
embA 4245699 p.Gly823Arg missense_variant 0.4
embB 4246689 p.Pro59Gln missense_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408420 c.-218C>A upstream_gene_variant 0.1