TB-Profiler result

Run: SRR023493
Summary

Run ID: SRR023493

Sample name:

Date: 02-04-2023 14:13:34

Number of reads: 398413

Percentage reads mapped: 97.61

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9060 p.Ala587Pro missense_variant 0.67
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490782 c.-1G>A upstream_gene_variant 0.22
fgd1 491591 p.Lys270Met missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 763834 p.Met155Ile missense_variant 0.4
rpoC 764558 p.Arg397Ser missense_variant 1.0
mmpL5 777817 p.Val222Ile missense_variant 0.4
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781738 p.Gln60Pro missense_variant 0.17
rplC 801369 c.561C>A synonymous_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
inhA 1674497 p.Pro99Gln missense_variant 0.2
rpsA 1834683 p.Ala381Asp missense_variant 0.4
katG 2156436 c.-325C>A upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448366 c.-138C>A upstream_gene_variant 0.67
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3640379 c.-164T>C upstream_gene_variant 1.0
clpC1 4038727 p.Thr660Ser missense_variant 0.25
embB 4248470 p.Gly653Ser missense_variant 0.5
aftB 4268083 p.Gln252* stop_gained 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0