TB-Profiler result

Run: SRR10808600

Summary

Run ID: SRR10808600

Sample name:

Date: 02-04-2023 19:01:24

Number of reads: 2310142

Percentage reads mapped: 99.79

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169041 c.1572G>A synonymous_variant 0.39
PPE35 2169044 c.1569G>C synonymous_variant 0.42
PPE35 2169047 p.Ile522Val missense_variant 0.31
PPE35 2169053 c.1560T>C synonymous_variant 1.0
PPE35 2169056 c.1557A>G synonymous_variant 0.31
PPE35 2169059 c.1554G>A synonymous_variant 0.69
PPE35 2169063 p.Met517Thr missense_variant 1.0
PPE35 2169065 p.Ala516Ile missense_variant 0.69
PPE35 2169068 c.1545G>T synonymous_variant 0.69
PPE35 2169071 c.1542A>G synonymous_variant 0.29
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
aftB 4268532 p.Thr102Ile missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0