TB-Profiler result

Run: SRR11444406

Summary

Run ID: SRR11444406

Sample name:

Date: 02-04-2023 21:07:57

Number of reads: 3921479

Percentage reads mapped: 98.54

Strain: lineage4.8

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 620095 p.His69Cys missense_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304185 p.Asp419Tyr missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rpsA 1834424 p.Gln295* stop_gained 0.11
rpsA 1834440 p.Lys300Met missense_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2222569 p.Ala199Val missense_variant 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2987055 c.218delT frameshift_variant 0.11
clpC1 4039729 p.Asp326Asn missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244858 c.1626G>A synonymous_variant 0.14
embB 4245779 c.-735C>A upstream_gene_variant 0.12
embB 4246694 c.186delG frameshift_variant 0.12
embB 4247799 p.Thr429Ile missense_variant 0.11
aftB 4267438 c.1399C>A synonymous_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0