TB-Profiler result

Run: SRR11972234

Summary

Run ID: SRR11972234

Sample name:

Date: 03-04-2023 05:32:55

Number of reads: 191741

Percentage reads mapped: 99.32

Strain:

Drug-resistance: Sensitive


Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1.2.1 Indo-Oceanic EAI2 RD239 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9260 c.1959G>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490883 p.Ser34Asn missense_variant 0.2
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575368 c.21T>C synonymous_variant 1.0
mshA 576501 p.Ile385Thr missense_variant 0.25
ccsA 619805 c.-86C>T upstream_gene_variant 0.33
rpoB 760380 p.Thr192Pro missense_variant 0.29
rpoB 762889 p.His1028Leu missense_variant 0.29
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763531 c.162G>C synonymous_variant 1.0
rpoC 763830 p.Glu154Ala missense_variant 0.33
rpoC 763884 p.Ala172Val missense_variant 1.0
rpoC 763886 c.517C>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 777119 p.His454Gln missense_variant 0.25
mmpL5 777122 c.1359C>T synonymous_variant 0.22
mmpL5 777128 c.1353A>G synonymous_variant 0.22
mmpL5 779046 c.-566G>A upstream_gene_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781654 p.Gly32Asp missense_variant 0.5
rplC 801345 p.Asn179Lys missense_variant 0.15
fbiC 1304571 c.1641G>A synonymous_variant 1.0
Rv1258c 1406312 c.1029T>C synonymous_variant 1.0
embR 1417019 p.Cys110Tyr missense_variant 1.0
atpE 1460907 c.-138T>C upstream_gene_variant 1.0
atpE 1460961 c.-84A>G upstream_gene_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473523 n.-135T>A upstream_gene_variant 0.25
rrl 1474306 n.649A>G non_coding_transcript_exon_variant 0.2
rrl 1474452 n.795C>T non_coding_transcript_exon_variant 0.18
fabG1 1673229 c.-211C>T upstream_gene_variant 1.0
fabG1 1673603 p.Leu55Pro missense_variant 0.33
fabG1 1674025 p.Glu196* stop_gained 0.22
inhA 1674162 c.-40C>T upstream_gene_variant 1.0
rpsA 1833563 p.Ser8Pro missense_variant 0.25
rpsA 1834481 p.Glu314* stop_gained 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918381 p.Val148Phe missense_variant 0.2
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155027 p.Gly362Asp missense_variant 0.2
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169333 p.Met427Lys missense_variant 0.17
PPE35 2170403 c.210C>G synonymous_variant 0.12
PPE35 2170406 c.207A>G synonymous_variant 0.12
Rv1979c 2221933 p.Ala411Val missense_variant 0.33
Rv1979c 2222000 p.Val389Met missense_variant 0.25
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2519048 p.Gly312Ser missense_variant 1.0
eis 2714615 p.Glu240Lys missense_variant 0.67
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
ahpC 2726120 c.-73C>A upstream_gene_variant 0.17
ahpC 2726231 c.39C>T synonymous_variant 0.2
folC 2746281 p.Ile440Leu missense_variant 0.5
folC 2746825 c.774G>T synonymous_variant 0.5
Rv2752c 3067064 c.-873A>G upstream_gene_variant 0.29
thyA 3073948 p.Pro175Leu missense_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339417 c.300A>G synonymous_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
whiB7 3568488 c.191delG frameshift_variant 1.0
fbiB 3640557 c.-978T>C upstream_gene_variant 1.0
alr 3840805 p.Ser206Pro missense_variant 0.33
alr 3841612 c.-193_-192insC upstream_gene_variant 0.15
rpoA 3878026 p.Arg161His missense_variant 0.14
rpoA 3878037 c.471C>T synonymous_variant 0.13
clpC1 4040517 p.Val63Ala missense_variant 1.0
clpC1 4040857 c.-153C>T upstream_gene_variant 0.25
embC 4239685 c.-178G>A upstream_gene_variant 0.4
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 1.0
embC 4241562 p.Arg567His missense_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242976 c.-257G>A upstream_gene_variant 0.4
embA 4243580 c.348G>A synonymous_variant 1.0
embA 4244420 c.1188G>C synonymous_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247506 c.993C>T synonymous_variant 0.12
embB 4247578 c.1065G>A synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
aftB 4268225 c.612G>A synonymous_variant 0.2
aftB 4268832 p.Val2Asp missense_variant 0.2
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ubiA 4269864 c.-32delG upstream_gene_variant 1.0
ethA 4326037 c.1437G>A synonymous_variant 0.18
ethA 4326975 p.Trp167Gly missense_variant 0.5
ethA 4327428 p.Gly16Ser missense_variant 0.25
whiB6 4338361 p.Arg54Gln missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0