TB-Profiler result

Run: SRR13837504
Summary

Run ID: SRR13837504

Sample name:

Date: 03-04-2023 09:11:58

Number of reads: 589495

Percentage reads mapped: 95.3

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6667 p.Gln476His missense_variant 1.0
gyrA 7289 c.-13_-12insT upstream_gene_variant 1.0
rpoB 760214 p.Asn136Lys missense_variant 1.0
fbiC 1304005 p.Pro359Ser missense_variant 1.0
rrs 1471943 n.98T>C non_coding_transcript_exon_variant 1.0
rrs 1472075 n.230A>C non_coding_transcript_exon_variant 1.0
rrs 1473066 n.1221A>T non_coding_transcript_exon_variant 1.0
rrs 1473370 n.1525T>C non_coding_transcript_exon_variant 0.92
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.12
fabG1 1673813 p.Arg125Leu missense_variant 1.0
inhA 1674784 p.Arg195Gly missense_variant 1.0
rpsA 1833664 c.123C>G synonymous_variant 0.1
rpsA 1833700 c.159C>T synonymous_variant 0.14
rpsA 1834240 c.699T>C synonymous_variant 0.11
rpsA 1834357 c.816T>C synonymous_variant 0.16
rpsA 1834366 c.825A>G synonymous_variant 0.12
rpsA 1834375 c.834G>C synonymous_variant 0.12
rpsA 1834396 c.855G>C synonymous_variant 0.15
rpsA 1834411 c.870T>G synonymous_variant 0.19
rpsA 1834414 c.873C>T synonymous_variant 0.18
rpsA 1834417 c.876G>C synonymous_variant 0.17
rpsA 1834423 c.882G>C synonymous_variant 0.17
rpsA 1834429 c.888C>T synonymous_variant 0.17
rpsA 1834438 c.897C>T synonymous_variant 0.15
rpsA 1834451 c.910T>C synonymous_variant 0.16
rpsA 1834456 c.915T>G synonymous_variant 0.17
rpsA 1834468 c.927A>G synonymous_variant 0.22
rpsA 1834477 c.936C>T synonymous_variant 0.18
rpsA 1834489 c.948T>C synonymous_variant 0.15
ndh 2101793 p.Trp417* stop_gained 1.0
PPE35 2169624 p.Gly330Asp missense_variant 1.0
kasA 2519223 p.Thr370Ile missense_variant 1.0
ahpC 2726213 c.21C>T synonymous_variant 1.0
ribD 2987016 p.Gly60Arg missense_variant 1.0
Rv2752c 3065644 p.Thr183Ser missense_variant 1.0
thyA 3074595 c.-124C>A upstream_gene_variant 1.0
alr 3841581 c.-161T>A upstream_gene_variant 1.0
rpoA 3878160 c.348C>G synonymous_variant 0.1
rpoA 3878169 c.339G>C synonymous_variant 0.11
rpoA 3878184 c.324C>T synonymous_variant 0.14
rpoA 3878193 c.315T>C synonymous_variant 0.14
rpoA 3878196 p.Glu104Ala missense_variant 0.14
rpoA 3878205 c.303T>C synonymous_variant 0.19
rpoA 3878217 c.291A>G synonymous_variant 0.15
rpoA 3878259 c.249G>C synonymous_variant 0.1
rpoA 3878271 c.237T>C synonymous_variant 0.14
rpoA 3878283 p.Glu75Asp missense_variant 0.12
rpoA 3878292 c.216T>C synonymous_variant 0.12
rpoA 3878322 c.186A>G synonymous_variant 0.1
clpC1 4038923 c.1782A>T synonymous_variant 0.12
embC 4242810 p.Leu983Gln missense_variant 1.0
embB 4246553 p.Arg14Trp missense_variant 1.0
embB 4248920 p.Val803Met missense_variant 1.0
embB 4249551 p.Arg1013Leu missense_variant 1.0
ethA 4326296 p.Leu393Gln missense_variant 1.0