TB-Profiler result

Run: SRR13837609
Summary

Run ID: SRR13837609

Sample name:

Date: 2024-10-03T18:39:42.934447

Number of reads: 293865

Percentage reads mapped: 98.01

Median coverage: 9.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
embR 1416901 c.447G>C synonymous_variant 1.0 ethambutol
rrl 1476589 n.2932G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
PPE35 2170487 c.126T>A synonymous_variant 1.0 pyrazinamide
ribD 2987369 c.531G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3073975 p.Arg166Pro missense_variant 1.0 para-aminosalicylic_acid
Rv3236c 3612013 c.1104A>T synonymous_variant 1.0 pyrazinamide
Rv3236c 3612032 p.Met362Arg missense_variant 1.0 pyrazinamide
embA 4244849 c.1617C>G synonymous_variant 1.0 ethambutol