TB-Profiler result

Run: SRR13837659
Summary

Run ID: SRR13837659

Sample name:

Date: 2024-10-05T14:21:10.191542

Number of reads: 293984

Percentage reads mapped: 99.06

Median coverage: 10.0

Strain: lineage4.9

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 1.0
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
dnaA 819 c.819C>A synonymous_variant 1.0 isoniazid
gyrA 6898 c.-404G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
mshA 575414 p.Gly23Ser missense_variant 1.0 isoniazid
ethionamide
embR 1417578 c.-231T>C upstream_gene_variant 1.0 ethambutol
bacA 2063871 p.Phe286Leu missense_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
ribD 2987136 p.Val100Ile missense_variant 1.0 para-aminosalicylic_acid
ribD 2987590 p.Leu251Arg missense_variant 1.0 para-aminosalicylic_acid
alr 3841281 p.His47Arg missense_variant 1.0 cycloserine