TB-Profiler result

Run: SRR13837708

Summary

Run ID: SRR13837708

Sample name:

Date: 03-04-2023 09:16:20

Number of reads: 293810

Percentage reads mapped: 97.0

Strain: lineage4.9

Drug-resistance: Other


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
embC 4240748 p.Tyr296His missense_variant 1.0 ethambutol
embB 4247959 p.Met482Ile missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
fgd1 491360 p.Ile193Ser missense_variant 1.0
mshA 576396 p.Ser350Ile missense_variant 1.0
rpoB 760225 p.Glu140Ala missense_variant 1.0
rpoC 767186 p.Gln1273* stop_gained 1.0
mmpR5 779067 p.Tyr26* stop_gained 1.0
rplC 800933 p.Pro42His missense_variant 1.0
fbiC 1305306 c.2376A>T synonymous_variant 1.0
tlyA 1918560 c.621G>T synonymous_variant 1.0
ndh 2102402 p.Leu214Arg missense_variant 1.0
katG 2156175 c.-64T>G upstream_gene_variant 1.0
PPE35 2169349 p.Phe422Ile missense_variant 1.0
PPE35 2170540 p.Leu25Val missense_variant 1.0
pncA 2288999 p.Phe81Leu missense_variant 1.0
fbiD 3339019 c.-99C>A upstream_gene_variant 0.15
fbiD 3339660 c.543C>G synonymous_variant 1.0
Rv3236c 3612627 p.Ala164Thr missense_variant 1.0
embA 4244119 p.Tyr296Phe missense_variant 1.0
embB 4247417 p.Tyr302Asn missense_variant 1.0
embB 4248036 p.Val508Gly missense_variant 1.0
embB 4248325 c.1812G>C synonymous_variant 1.0
aftB 4267894 p.Ile315Phe missense_variant 1.0
ethA 4326052 p.Asp474Glu missense_variant 1.0
ethA 4327388 p.Thr29Ile missense_variant 1.0
ethR 4328162 p.His205Pro missense_variant 1.0
whiB6 4338518 c.4C>A synonymous_variant 1.0