TB-Profiler result

Run: SRR13837976
Summary

Run ID: SRR13837976

Sample name:

Date: 03-04-2023 09:23:24

Number of reads: 884414

Percentage reads mapped: 97.32

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5709 p.Gly157Val missense_variant 1.0
gyrA 9028 p.Val576Ala missense_variant 0.91
gyrA 9191 c.1890G>C synonymous_variant 0.1
gyrA 9308 p.Asp669Glu missense_variant 0.12
rpoB 762011 c.2205G>C synonymous_variant 0.97
rpoB 762279 c.2474delA frameshift_variant 1.0
mmpS5 778823 p.Ile28Thr missense_variant 1.0
fbiC 1304640 c.1710A>C synonymous_variant 1.0
Rv1258c 1406376 p.Gly322Val missense_variant 1.0
PPE35 2169882 p.Ser244Ile missense_variant 1.0
eis 2714940 c.392delA frameshift_variant 1.0
ald 3087311 c.492C>G synonymous_variant 1.0
fbiB 3642465 p.Asp311His missense_variant 1.0
alr 3840300 p.Pro374His missense_variant 1.0
rpoA 3878288 p.Thr74Pro missense_variant 1.0
clpC1 4039415 c.1289dupA frameshift_variant 1.0
clpC1 4040792 c.-88A>T upstream_gene_variant 1.0
embA 4243235 c.3G>T synonymous_variant 1.0