TB-Profiler result

Run: SRR13861319

Summary

Run ID: SRR13861319

Sample name:

Date: 03-04-2023 09:28:50

Number of reads: 209202

Percentage reads mapped: 6.98

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6330 p.Glu364Gly missense_variant 0.22
fgd1 490804 p.Tyr8Asn missense_variant 1.0
fgd1 490893 c.111C>T synonymous_variant 1.0
mshA 575498 p.Ala51Pro missense_variant 1.0
rpoC 763663 c.294C>A synonymous_variant 1.0
rpoC 763955 p.Lys196Gln missense_variant 1.0
rpoC 765682 p.Asn771Lys missense_variant 1.0
rpoC 766342 c.2973C>A synonymous_variant 1.0
rpsL 781579 p.Leu7Arg missense_variant 1.0
embR 1416509 p.Arg280Pro missense_variant 1.0
rrl 1474164 n.507C>A non_coding_transcript_exon_variant 1.0
inhA 1674315 c.114C>G synonymous_variant 1.0
katG 2154959 c.1153C>A synonymous_variant 1.0
PPE35 2170236 c.376_377insG frameshift_variant 1.0
pncA 2290061 c.-820C>T upstream_gene_variant 1.0
folC 2747798 c.-200A>T upstream_gene_variant 1.0
pepQ 2860252 p.Thr56Ser missense_variant 1.0
Rv2752c 3065651 p.Arg181Gly missense_variant 1.0
Rv3083 3448855 p.Val118Ile missense_variant 1.0
rpoA 3877765 p.Ala248Gly missense_variant 1.0
ddn 3986847 c.4_5insA frameshift_variant 1.0
embB 4247059 c.546C>G synonymous_variant 1.0
embB 4247144 p.Ser211Pro missense_variant 1.0
ubiA 4269553 p.Ala94Gly missense_variant 1.0
gid 4408259 c.-57G>C upstream_gene_variant 1.0