TB-Profiler result

Run: SRR13861699
Summary

Run ID: SRR13861699

Sample name:

Date: 03-04-2023 09:38:23

Number of reads: 327479

Percentage reads mapped: 32.78

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5532 c.295dupG frameshift_variant 1.0
gyrB 5832 p.Ala198Gly missense_variant 1.0
gyrB 6209 c.970C>T synonymous_variant 0.15
gyrB 6214 c.975G>C synonymous_variant 0.15
gyrB 6217 c.978G>C synonymous_variant 0.15
gyrB 6223 c.984G>C synonymous_variant 0.17
gyrB 6242 p.Arg335Lys missense_variant 0.18
gyrB 6250 c.1011A>G synonymous_variant 0.18
gyrB 6253 c.1014G>C synonymous_variant 0.17
gyrB 6280 c.1041T>C synonymous_variant 0.13
gyrB 6286 c.1047T>C synonymous_variant 0.15
gyrB 6292 c.1053G>C synonymous_variant 0.15
gyrA 6976 c.-326A>G upstream_gene_variant 1.0
gyrA 8069 c.768T>C synonymous_variant 0.22
gyrA 8078 c.777A>G synonymous_variant 0.22
gyrA 8090 c.789C>G synonymous_variant 0.2
gyrA 8096 c.795T>C synonymous_variant 0.2
gyrA 8099 c.798T>C synonymous_variant 0.2
gyrA 8111 c.810G>C synonymous_variant 0.22
gyrA 8156 c.855T>C synonymous_variant 0.29
gyrA 8168 c.867A>G synonymous_variant 0.29
gyrA 8174 c.873C>G synonymous_variant 0.29
gyrA 8177 c.876A>C synonymous_variant 0.29
gyrA 8198 c.897T>C synonymous_variant 0.38
gyrA 8204 c.903C>T synonymous_variant 0.38
gyrA 8207 c.906T>C synonymous_variant 0.38
gyrA 8216 c.915G>A synonymous_variant 0.29
gyrA 8219 c.918T>C synonymous_variant 0.29
gyrA 8225 c.924T>C synonymous_variant 0.29
gyrA 8234 c.933T>G synonymous_variant 0.25
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.25
gyrA 8253 p.Ile318Leu missense_variant 0.29
gyrA 8264 c.963T>C synonymous_variant 0.25
gyrA 8267 c.966G>C synonymous_variant 0.25
gyrA 8270 c.969G>C synonymous_variant 0.25
gyrA 8283 p.Ile328Leu missense_variant 0.29
gyrA 8288 c.987T>C synonymous_variant 0.33
gyrA 8294 c.993T>C synonymous_variant 0.33
gyrA 8324 c.1023T>C synonymous_variant 0.33
ccsA 619735 c.-156G>C upstream_gene_variant 1.0
ccsA 620100 c.210G>T synonymous_variant 1.0
ccsA 620245 c.355T>C synonymous_variant 0.14
ccsA 620249 p.Ser120Cys missense_variant 0.14
ccsA 620254 c.364_366delCTCinsTTG synonymous_variant 0.14
ccsA 620265 c.375C>G synonymous_variant 0.17
ccsA 620269 p.Val127Ile missense_variant 0.15
ccsA 620275 c.385C>T synonymous_variant 0.15
ccsA 620283 c.393T>C synonymous_variant 0.14
ccsA 620284 p.Ala132Pro missense_variant 0.14
ccsA 620288 p.Arg133Gln missense_variant 0.14
ccsA 620307 c.417C>G synonymous_variant 0.15
ccsA 620317 p.Val143Leu missense_variant 0.15
ccsA 620331 c.441C>T synonymous_variant 0.13
ccsA 620340 c.450C>G synonymous_variant 0.15
rpoB 759609 c.-198C>A upstream_gene_variant 0.86
rpoB 759644 c.-163T>A upstream_gene_variant 0.18
rpoB 759647 c.-160T>C upstream_gene_variant 0.18
rpoB 759655 c.-151delA upstream_gene_variant 0.17
rpoB 759659 c.-148_-147insGA upstream_gene_variant 0.18
rpoB 759662 c.-145C>T upstream_gene_variant 0.18
rpoB 759667 c.-140C>T upstream_gene_variant 0.2
rpoB 759670 c.-137C>T upstream_gene_variant 0.2
rpoB 759671 c.-136G>T upstream_gene_variant 0.18
rpoB 759672 c.-135G>C upstream_gene_variant 0.18
rpoB 759683 c.-124T>C upstream_gene_variant 0.15
rpoB 759701 c.-106A>T upstream_gene_variant 0.14
rpoB 760611 c.805T>C synonymous_variant 0.13
rpoB 760646 c.840C>G synonymous_variant 0.13
rpoB 760661 c.855A>C synonymous_variant 0.12
rpoB 760793 c.987A>G synonymous_variant 0.17
rpoB 760805 c.999G>C synonymous_variant 0.17
rpoB 760817 c.1011A>G synonymous_variant 0.2
rpoB 760820 c.1014T>C synonymous_variant 0.19
rpoB 760826 c.1020C>G synonymous_variant 0.19
rpoB 760830 c.1024T>C synonymous_variant 0.13
rpoB 760845 p.Thr347Pro missense_variant 0.13
rpoB 760859 c.1053T>C synonymous_variant 0.2
rpoB 760869 p.Val355Ile missense_variant 0.18
rpoB 760886 c.1080A>G synonymous_variant 0.17
rpoB 760919 c.1113C>G synonymous_variant 0.17
rpoB 760925 c.1119T>C synonymous_variant 0.17
rpoB 761133 c.1327_1329delTTGinsCTC synonymous_variant 0.15
rpoB 761150 c.1344A>C synonymous_variant 0.15
rpoB 761165 c.1359G>C synonymous_variant 0.17
rpoB 761168 c.1362C>G synonymous_variant 0.15
rpoB 761180 c.1374A>C synonymous_variant 0.14
rpoB 761847 p.Cys681Ser missense_variant 0.12
rpoB 761852 c.2046C>G synonymous_variant 0.14
rpoB 761858 c.2052G>C synonymous_variant 0.14
rpoB 761864 c.2058G>C synonymous_variant 0.14
rpoB 761873 c.2067A>G synonymous_variant 0.17
rpoB 761885 c.2079T>C synonymous_variant 0.17
rpoB 761891 c.2085G>C synonymous_variant 0.18
rpoB 761906 c.2100C>G synonymous_variant 0.2
rpoB 761909 c.2103T>C synonymous_variant 0.2
rpoB 761912 c.2106T>C synonymous_variant 0.18
rpoB 761915 p.Asp703Glu missense_variant 0.18
rpoB 761916 p.Asp704Asn missense_variant 0.17
rpoB 761948 c.2142G>C synonymous_variant 0.17
rpoB 761954 c.2148C>G synonymous_variant 0.17
rpoB 762014 c.2208C>T synonymous_variant 0.2
rpoC 762860 c.-510G>C upstream_gene_variant 0.18
rpoC 762863 c.-507T>C upstream_gene_variant 0.18
rpoC 762929 c.-441G>C upstream_gene_variant 0.22
rpoC 762995 c.-375G>T upstream_gene_variant 0.17
rpoC 763050 c.-320C>T upstream_gene_variant 1.0
rpoC 764405 c.1036A>C synonymous_variant 0.18
rpoC 764434 c.1065A>G synonymous_variant 0.21
rpoC 764441 p.Ile358Leu missense_variant 0.15
rpoC 764446 c.1077T>C synonymous_variant 0.23
rpoC 764455 c.1086G>T synonymous_variant 0.14
rpoC 764461 p.Glu364Asp missense_variant 0.17
rpoC 764470 c.1101C>G synonymous_variant 0.15
rpoC 764471 p.Asn368Arg missense_variant 0.15
rpoC 764479 c.1110G>A synonymous_variant 0.15
rpoC 764485 c.1116G>C synonymous_variant 0.15
rpoC 764498 p.Ser377Ala missense_variant 0.15
rpoC 764503 c.1134G>C synonymous_variant 0.17
rpoC 764509 c.1140G>C synonymous_variant 0.2
rpoC 764513 p.Phe382Leu missense_variant 0.2
rpoC 764521 c.1152T>C synonymous_variant 0.22
rpoC 764752 c.1383G>C synonymous_variant 0.14
rpoC 764872 c.1503A>G synonymous_variant 0.13
rpoC 764893 c.1524T>C synonymous_variant 0.12
rpoC 764932 c.1563C>A synonymous_variant 0.18
rpoC 764968 c.1599T>C synonymous_variant 0.19
rpoC 764995 c.1626C>G synonymous_variant 0.2
rpoC 765007 c.1638T>G synonymous_variant 0.2
rpoC 765019 c.1650A>G synonymous_variant 0.2
rpoC 765022 c.1653G>C synonymous_variant 0.14
rpoC 765034 c.1665T>C synonymous_variant 0.17
rpoC 766447 c.3078T>C synonymous_variant 0.22
rpoC 766549 c.3180G>C synonymous_variant 0.2
rpoC 766583 p.Gly1072Ser missense_variant 0.18
rpoC 766750 c.3381C>G synonymous_variant 0.2
rpoC 766765 c.3396A>C synonymous_variant 0.17
rpoC 766774 c.3405T>C synonymous_variant 0.18
rpoC 766801 c.3432C>A synonymous_variant 0.18
rpoC 766804 c.3435A>G synonymous_variant 0.18
mmpL5 776796 p.Val562Ala missense_variant 1.0
mmpS5 778642 p.Trp88* stop_gained 1.0
rplC 800612 c.-197A>G upstream_gene_variant 0.17
rplC 800618 c.-191T>C upstream_gene_variant 0.17
rplC 800648 c.-161A>C upstream_gene_variant 0.14
rplC 800654 c.-155T>C upstream_gene_variant 0.14
rplC 800715 c.-94A>C upstream_gene_variant 0.14
rplC 800720 c.-89T>C upstream_gene_variant 0.14
rplC 800723 c.-86C>G upstream_gene_variant 0.14
rplC 801127 p.Ala107Thr missense_variant 0.2
rplC 801132 c.324T>C synonymous_variant 0.2
rplC 801147 c.339T>C synonymous_variant 0.33
rplC 801150 c.342G>C synonymous_variant 0.33
rplC 801153 c.345G>C synonymous_variant 0.33
rplC 801156 c.348T>A synonymous_variant 0.29
rplC 801171 c.363A>G synonymous_variant 0.25
rplC 801174 c.366T>C synonymous_variant 0.29
fbiC 1303632 c.702T>G synonymous_variant 0.14
fbiC 1303818 c.888C>G synonymous_variant 0.29
fbiC 1303836 c.906G>C synonymous_variant 0.25
fbiC 1303845 c.915C>G synonymous_variant 0.25
fbiC 1303846 p.Phe306Val missense_variant 0.22
fbiC 1303854 c.924T>C synonymous_variant 0.25
fbiC 1303860 c.930A>C synonymous_variant 0.25
fbiC 1303881 c.951G>C synonymous_variant 0.33
fbiC 1303884 c.954T>G synonymous_variant 0.33
fbiC 1303911 c.981G>C synonymous_variant 0.5
fbiC 1303914 c.984C>G synonymous_variant 0.5
fbiC 1303920 c.990C>G synonymous_variant 0.4
fbiC 1303923 c.993C>T synonymous_variant 0.33
fbiC 1303929 c.999G>C synonymous_variant 0.33
fbiC 1303947 c.1017T>C synonymous_variant 0.33
fbiC 1303948 p.Gly340Arg missense_variant 0.33
fbiC 1303969 p.Val347Ile missense_variant 0.33
fbiC 1303973 p.Gly348Ala missense_variant 0.33
fbiC 1303995 c.1065C>T synonymous_variant 0.57
fbiC 1304001 c.1071C>G synonymous_variant 0.67
fbiC 1304008 c.1078T>C synonymous_variant 0.67
fbiC 1304034 c.1104A>G synonymous_variant 0.5
fbiC 1304040 c.1110C>G synonymous_variant 0.5
fbiC 1304046 c.1116C>G synonymous_variant 0.5
fbiC 1304049 c.1119T>G synonymous_variant 0.5
fbiC 1304058 c.1128G>A synonymous_variant 0.5
fbiC 1304059 c.1129C>T synonymous_variant 0.5
fbiC 1304064 c.1134G>C synonymous_variant 0.5
fbiC 1304067 c.1137G>C synonymous_variant 0.5
fbiC 1304073 c.1143C>T synonymous_variant 0.67
fbiC 1304080 p.Ala384Ser missense_variant 0.57
fbiC 1304091 p.Asp387Glu missense_variant 0.43
fbiC 1304092 p.Met388Leu missense_variant 0.43
fbiC 1304097 c.1167G>C synonymous_variant 0.43
fbiC 1304115 c.1185A>G synonymous_variant 0.5
fbiC 1304127 c.1197A>G synonymous_variant 0.5
fbiC 1304136 c.1206C>T synonymous_variant 0.43
fbiC 1304142 c.1212G>C synonymous_variant 0.29
fbiC 1304161 p.Arg411Ser missense_variant 0.33
fbiC 1304166 c.1236A>G synonymous_variant 0.33
fbiC 1304172 c.1242G>C synonymous_variant 0.5
fbiC 1304173 p.Val415Arg missense_variant 0.33
fbiC 1304184 c.1254G>C synonymous_variant 0.33
fbiC 1304192 p.Ala421Val missense_variant 0.33
fbiC 1304199 c.1269C>T synonymous_variant 0.33
fbiC 1304628 c.1698G>C synonymous_variant 0.15
fbiC 1304634 c.1704C>G synonymous_variant 0.15
fbiC 1304640 c.1710A>C synonymous_variant 0.15
Rv1258c 1407009 p.Ala111Asp missense_variant 1.0
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.17
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.17
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.2
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.22
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.2
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.18
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.18
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.18
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.18
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.14
rrl 1474104 n.447G>A non_coding_transcript_exon_variant 0.14
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.14
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.14
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.21
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.25
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.3
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.33
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.22
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.22
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.18
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.2
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.18
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.14
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.12
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.2
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.25
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.5
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.57
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.57
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.57
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.59
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.57
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.59
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.55
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.59
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.59
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.5
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.54
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.57
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.57
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.54
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.54
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.5
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.45
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.47
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.47
inhA 1674582 c.381T>C synonymous_variant 0.14
inhA 1674585 c.384T>C synonymous_variant 0.14
inhA 1674589 p.Met130Leu missense_variant 0.15
inhA 1674654 c.453G>C synonymous_variant 0.13
inhA 1674703 c.502T>C synonymous_variant 0.14
inhA 1674891 p.Trp230Cys missense_variant 1.0
rpsA 1833568 c.27G>C synonymous_variant 0.14
rpsA 1833589 c.48A>T synonymous_variant 0.14
rpsA 1833595 c.54T>C synonymous_variant 0.14
rpsA 1833619 c.78A>C synonymous_variant 0.14
rpsA 1833661 c.120A>G synonymous_variant 0.25
rpsA 1833667 c.126C>G synonymous_variant 0.2
rpsA 1833724 c.183C>G synonymous_variant 0.22
rpsA 1833727 c.186G>C synonymous_variant 0.24
rpsA 1833742 c.201A>G synonymous_variant 0.27
rpsA 1833745 c.204G>C synonymous_variant 0.27
rpsA 1833787 c.246C>G synonymous_variant 0.27
rpsA 1833790 c.249T>A synonymous_variant 0.29
rpsA 1833799 c.258C>G synonymous_variant 0.23
rpsA 1833811 c.270G>C synonymous_variant 0.15
rpsA 1833838 c.297G>C synonymous_variant 0.17
rpsA 1833841 c.300C>G synonymous_variant 0.18
rpsA 1833847 c.306C>G synonymous_variant 0.17
rpsA 1833856 c.315A>G synonymous_variant 0.31
rpsA 1833862 c.321G>T synonymous_variant 0.2
rpsA 1833874 c.333T>C synonymous_variant 0.18
rpsA 1833928 c.387G>C synonymous_variant 0.18
rpsA 1833940 c.399C>G synonymous_variant 0.17
rpsA 1833970 c.429G>C synonymous_variant 0.17
rpsA 1833979 c.438T>C synonymous_variant 0.17
tlyA 1918625 p.Pro229Leu missense_variant 1.0
ndh 2101906 c.1137G>C synonymous_variant 0.17
ndh 2101924 c.1119T>G synonymous_variant 0.17
Rv1979c 2222721 c.444G>C synonymous_variant 1.0
ahpC 2726345 p.Phe51Leu missense_variant 1.0
ahpC 2726591 c.399C>G synonymous_variant 0.2
ahpC 2726593 p.Val134Ala missense_variant 0.2
ahpC 2726600 c.408T>C synonymous_variant 0.2
ahpC 2726612 c.420C>G synonymous_variant 0.22
ahpC 2726638 p.Ala149Val missense_variant 0.22
ahpC 2726645 c.453C>G synonymous_variant 0.22
ahpC 2726657 c.465A>C synonymous_variant 0.2
ahpC 2726669 p.Asp159Glu missense_variant 0.18
ahpC 2726672 c.480G>A synonymous_variant 0.18
ahpC 2726675 c.483A>G synonymous_variant 0.18
ahpC 2726681 c.489A>G synonymous_variant 0.18
ahpC 2726687 c.495C>G synonymous_variant 0.18
ahpC 2726690 c.498C>T synonymous_variant 0.18
ahpC 2726693 c.501C>G synonymous_variant 0.2
ahpC 2726696 c.504C>G synonymous_variant 0.2
ahpC 2726717 c.525A>G synonymous_variant 0.15
ribD 2987230 p.Ala131Val missense_variant 0.25
Rv2752c 3065166 c.1026C>G synonymous_variant 0.22
Rv2752c 3065997 c.195C>G synonymous_variant 0.13
Rv2752c 3066002 p.Met64Leu missense_variant 0.15
Rv2752c 3066024 c.168T>C synonymous_variant 0.17
Rv2752c 3066040 p.Gly51Thr missense_variant 0.33
Rv2752c 3066042 c.150T>C synonymous_variant 0.22
Rv2752c 3066050 p.Leu48Met missense_variant 0.22
Rv2752c 3066054 c.138T>G synonymous_variant 0.22
Rv2752c 3066066 c.126T>C synonymous_variant 0.18
Rv2752c 3066075 c.117A>G synonymous_variant 0.18
Rv2752c 3066087 c.105A>G synonymous_variant 0.17
Rv2752c 3066118 p.Asn25Ser missense_variant 0.17
Rv2752c 3067095 c.-904G>C upstream_gene_variant 1.0
thyX 3067220 c.726G>C synonymous_variant 0.29
thyX 3067223 c.723G>C synonymous_variant 0.29
thyX 3067244 c.702C>G synonymous_variant 0.29
thyX 3067249 p.Thr233Ala missense_variant 0.33
thyX 3067250 p.Val232Ile missense_variant 0.33
thyX 3067277 c.669C>G synonymous_variant 0.22
thyX 3067280 c.666G>C synonymous_variant 0.22
thyX 3067284 p.Ala221Asp missense_variant 0.22
thyX 3067286 c.660C>G synonymous_variant 0.22
thyX 3067289 c.657C>G synonymous_variant 0.2
thyX 3067293 p.Gln218Arg missense_variant 0.2
thyX 3067304 c.642A>G synonymous_variant 0.18
thyX 3067316 c.630A>G synonymous_variant 0.2
thyX 3067325 c.621A>G synonymous_variant 0.22
thyX 3067355 c.591A>C synonymous_variant 0.25
thyX 3067493 c.453A>G synonymous_variant 0.14
thyX 3067500 p.Lys149Arg missense_variant 0.14
thyA 3073794 c.678A>C synonymous_variant 0.25
thyA 3073827 c.645A>G synonymous_variant 0.2
thyA 3073839 c.633T>C synonymous_variant 0.2
thyA 3073872 p.Ile200Val missense_variant 0.2
thyA 3073878 c.594G>A synonymous_variant 0.22
thyA 3073892 c.580T>C synonymous_variant 0.22
thyA 3073893 c.579C>G synonymous_variant 0.22
thyA 3073925 c.547T>C synonymous_variant 0.33
thyA 3073926 c.546G>C synonymous_variant 0.33
thyA 3073929 c.543T>C synonymous_variant 0.33
thyA 3073953 c.519T>C synonymous_variant 0.3
thyA 3073977 c.495A>G synonymous_variant 0.18
thyA 3073989 c.483T>C synonymous_variant 0.18
thyA 3074001 c.471C>G synonymous_variant 0.18
thyA 3074004 c.468T>C synonymous_variant 0.18
thyA 3074010 c.462C>G synonymous_variant 0.23
thyA 3074031 c.441T>C synonymous_variant 0.2
thyA 3074037 c.435C>G synonymous_variant 0.2
thyA 3074056 p.Glu139Pro missense_variant 0.18
thyA 3074061 c.411A>G synonymous_variant 0.18
thyA 3074076 c.396C>G synonymous_variant 0.17
Rv3083 3448912 p.Ile137Phe missense_variant 1.0
fprA 3474133 p.Pro43Thr missense_variant 1.0
whiB7 3568676 p.Ser2Ala missense_variant 1.0
fbiB 3642677 c.1143A>G synonymous_variant 0.27
fbiB 3642696 c.1162C>T synonymous_variant 0.22
fbiB 3642701 c.1167C>G synonymous_variant 0.25
alr 3840783 c.637_638insT frameshift_variant 1.0
rpoA 3877818 c.690A>G synonymous_variant 0.18
rpoA 3877839 c.669G>C synonymous_variant 0.25
rpoA 3877857 c.651G>A synonymous_variant 0.3
rpoA 3877866 c.642G>C synonymous_variant 0.27
rpoA 3877872 c.636C>T synonymous_variant 0.25
rpoA 3877875 c.633T>G synonymous_variant 0.25
rpoA 3877899 p.Ser203Thr missense_variant 0.17
rpoA 3877905 c.603A>G synonymous_variant 0.15
rpoA 3877908 p.Asn200Ser missense_variant 0.15
rpoA 3877953 c.555G>A synonymous_variant 0.2
rpoA 3877962 c.546G>T synonymous_variant 0.23
rpoA 3877986 c.522G>C synonymous_variant 0.14
rpoA 3877989 c.519A>G synonymous_variant 0.14
rpoA 3878022 c.486T>C synonymous_variant 0.17
rpoA 3878025 c.483C>T synonymous_variant 0.17
rpoA 3878031 c.477T>C synonymous_variant 0.15
rpoA 3878040 c.468T>C synonymous_variant 0.15
rpoA 3878046 c.462T>C synonymous_variant 0.14
rpoA 3878049 c.459G>C synonymous_variant 0.15
rpoA 3878055 c.453A>G synonymous_variant 0.15
ddn 3986648 c.-196C>G upstream_gene_variant 0.25
ddn 3986655 c.-189A>T upstream_gene_variant 0.27
ddn 3986660 c.-184C>T upstream_gene_variant 0.21
ddn 3986665 c.-179G>C upstream_gene_variant 0.21
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.21
ddn 3986681 c.-163C>G upstream_gene_variant 0.2
ddn 3986690 c.-154C>G upstream_gene_variant 0.2
ddn 3986696 c.-148G>T upstream_gene_variant 0.19
ddn 3986699 c.-145C>G upstream_gene_variant 0.2
clpC1 4038271 p.Pro812Ala missense_variant 0.25
clpC1 4038272 p.Gly811Ser missense_variant 0.25
clpC1 4038278 c.2427T>C synonymous_variant 0.25
clpC1 4038293 c.2412G>C synonymous_variant 0.2
clpC1 4038302 c.2403C>G synonymous_variant 0.2
clpC1 4038308 p.Val799Ile missense_variant 0.25
clpC1 4038317 c.2388G>C synonymous_variant 0.18
clpC1 4038326 p.Glu793Asp missense_variant 0.83
clpC1 4038359 c.2346A>G synonymous_variant 0.14
clpC1 4038368 c.2337T>C synonymous_variant 0.15
clpC1 4038388 c.2317T>C synonymous_variant 0.17
clpC1 4038398 c.2307G>T synonymous_variant 0.17
clpC1 4038498 p.Ser736Thr missense_variant 0.14
clpC1 4038530 p.Glu725Asp missense_variant 0.13
clpC1 4038536 c.2169C>T synonymous_variant 0.13
clpC1 4038596 c.2109A>G synonymous_variant 0.2
clpC1 4038611 c.2094C>T synonymous_variant 0.2
clpC1 4038623 c.2082A>G synonymous_variant 0.25
clpC1 4038640 p.Asp689Asn missense_variant 0.27
clpC1 4038653 c.2052C>T synonymous_variant 0.22
clpC1 4038658 p.Lys683Gln missense_variant 0.22
clpC1 4038740 c.1965G>C synonymous_variant 0.2
clpC1 4038748 p.Arg653Cys missense_variant 0.2
clpC1 4038755 c.1950G>C synonymous_variant 0.2
clpC1 4038773 c.1932T>C synonymous_variant 0.25
clpC1 4038782 c.1923G>C synonymous_variant 0.18
clpC1 4038790 c.1915C>T synonymous_variant 0.2
clpC1 4038812 c.1893T>C synonymous_variant 0.17
clpC1 4038815 c.1890G>T synonymous_variant 0.17
clpC1 4038851 c.1854G>A synonymous_variant 0.18
clpC1 4038878 c.1827A>G synonymous_variant 0.3
clpC1 4038908 c.1797C>G synonymous_variant 0.27
clpC1 4038914 c.1791G>C synonymous_variant 0.27
clpC1 4038923 c.1782A>G synonymous_variant 0.2
clpC1 4038932 c.1773G>C synonymous_variant 0.22
clpC1 4038953 c.1752A>G synonymous_variant 0.2
clpC1 4038956 c.1749T>C synonymous_variant 0.2
clpC1 4038965 c.1740T>C synonymous_variant 0.2
clpC1 4038971 c.1734T>C synonymous_variant 0.2
clpC1 4038974 c.1731T>C synonymous_variant 0.2
clpC1 4038989 c.1716T>C synonymous_variant 0.2
clpC1 4038997 c.1708T>C synonymous_variant 0.17
clpC1 4040021 c.684A>C synonymous_variant 0.17
clpC1 4040024 c.681A>G synonymous_variant 0.17
clpC1 4040033 c.672G>C synonymous_variant 0.17
clpC1 4040036 c.669C>G synonymous_variant 0.18
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.25
clpC1 4040093 c.612C>G synonymous_variant 0.25
clpC1 4040105 c.600C>G synonymous_variant 0.29
clpC1 4040147 c.558A>G synonymous_variant 0.43
clpC1 4040201 c.504C>G synonymous_variant 0.5
clpC1 4040207 c.498T>C synonymous_variant 0.5
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.5
clpC1 4040225 c.480A>C synonymous_variant 0.5
clpC1 4040228 c.477G>C synonymous_variant 0.5
clpC1 4040234 c.471C>G synonymous_variant 0.5
clpC1 4040237 c.468C>T synonymous_variant 0.5
clpC1 4040249 c.456A>G synonymous_variant 0.43
clpC1 4040273 c.432T>C synonymous_variant 0.5
clpC1 4040411 c.294T>C synonymous_variant 0.25
clpC1 4040423 c.282A>G synonymous_variant 0.22
clpC1 4040426 c.279T>C synonymous_variant 0.22
clpC1 4040441 c.264C>G synonymous_variant 0.2
clpC1 4040444 c.261C>G synonymous_variant 0.18
clpC1 4040450 c.255A>G synonymous_variant 0.18
clpC1 4040459 c.246C>G synonymous_variant 0.18
clpC1 4040465 c.240T>C synonymous_variant 0.17
clpC1 4040471 c.234T>C synonymous_variant 0.14
clpC1 4040477 c.228G>A synonymous_variant 0.15
clpC1 4040480 c.225T>C synonymous_variant 0.15
clpC1 4040522 c.183T>C synonymous_variant 0.15
clpC1 4040531 c.174T>C synonymous_variant 0.14
clpC1 4040534 c.171A>G synonymous_variant 0.14
clpC1 4040546 c.159G>C synonymous_variant 0.13
embC 4241026 c.1164C>G synonymous_variant 1.0
embA 4242250 c.-983C>G upstream_gene_variant 1.0
embA 4242760 c.-473G>C upstream_gene_variant 0.18
embA 4245077 c.1845G>C synonymous_variant 0.15
embA 4245083 c.1851A>C synonymous_variant 0.17
embA 4245089 c.1857G>C synonymous_variant 0.17
embA 4245092 c.1860C>G synonymous_variant 0.17
embA 4245101 c.1869G>C synonymous_variant 0.18
embA 4245137 c.1905T>C synonymous_variant 0.25
embA 4245149 c.1917C>G synonymous_variant 0.25
embA 4245182 c.1950T>C synonymous_variant 0.29
embB 4247398 c.885G>T synonymous_variant 0.91
embB 4249328 p.Met939Leu missense_variant 1.0
aftB 4267490 c.1347G>C synonymous_variant 1.0
ethA 4326203 p.Ser424* stop_gained 1.0