TB-Profiler result

Run: SRR14781853
Summary

Run ID: SRR14781853

Sample name:

Date: 03-04-2023 11:01:57

Number of reads: 3319174

Percentage reads mapped: 99.67

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.24
mshA 576482 p.Val379Leu missense_variant 0.15
rpoC 766085 p.Pro906Ala missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460992 c.-53A>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rpsA 1834028 p.Pro163Ser missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.18
fbiD 3339734 p.Ala206Gly missense_variant 0.65
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
fbiB 3641895 c.361C>T synonymous_variant 0.99
alr 3840764 c.657G>C synonymous_variant 1.0
rpoA 3878637 c.-130G>C upstream_gene_variant 0.43
rpoA 3878641 c.-134C>G upstream_gene_variant 0.45
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245511 p.Pro760Leu missense_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.29
embB 4248319 c.1806A>T synonymous_variant 0.24
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0