TB-Profiler result

Run: SRR14801289
Summary

Run ID: SRR14801289

Sample name:

Date: 03-04-2023 11:41:20

Number of reads: 5529111

Percentage reads mapped: 99.45

Strain: lineage4.2.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.1 Euro-American (TUR) H3;H4 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.99
gyrA 9121 p.Arg607His missense_variant 0.99
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576442 p.Cys365Trp missense_variant 0.22
mshA 576613 c.1266A>C synonymous_variant 0.26
mshA 576616 c.1269G>C synonymous_variant 0.28
rpoC 764367 p.Gly333Ala missense_variant 0.26
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.29
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.3
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169879 p.Phe245Cys missense_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.16
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.22
pepQ 2860159 p.Ala87Gly missense_variant 0.16
Rv2752c 3065832 c.360C>T synonymous_variant 0.99
ald 3086742 c.-78A>C upstream_gene_variant 0.99
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087816 p.Cys333Gly missense_variant 0.14
fbiD 3339734 p.Ala206Gly missense_variant 0.38
fbiD 3339749 p.Val211Gly missense_variant 0.2
fbiD 3339751 p.Ala212Pro missense_variant 0.18
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.99
whiB7 3568428 c.252A>G synonymous_variant 0.44
whiB7 3568431 c.249C>G synonymous_variant 0.25
alr 3841612 c.-193_-192insC upstream_gene_variant 1.0
rpoA 3878630 c.-123G>C upstream_gene_variant 0.29
rpoA 3878641 c.-134C>G upstream_gene_variant 0.62
panD 4044424 c.-143A>G upstream_gene_variant 0.99
embC 4240409 p.Pro183Ala missense_variant 0.25
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.48
embB 4246529 p.Ser6Gly missense_variant 0.25
embB 4248212 p.Ala567Thr missense_variant 0.98
embB 4249594 c.3081G>A synonymous_variant 0.99
ethA 4327779 c.-306G>A upstream_gene_variant 0.99
ethA 4328376 c.-903G>C upstream_gene_variant 0.99
whiB6 4338595 c.-75delG upstream_gene_variant 1.0