TB-Profiler result

Run: SRR14801620
Summary

Run ID: SRR14801620

Sample name:

Date: 03-04-2023 11:55:31

Number of reads: 4528024

Percentage reads mapped: 99.7

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 0.99
rpoC 767205 p.Arg1279His missense_variant 0.96
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.98
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2155321 p.Ala264Val missense_variant 0.98
katG 2156259 c.-148T>C upstream_gene_variant 0.98
PPE35 2168149 p.Pro822Ser missense_variant 0.95
PPE35 2170065 p.Ala183Gly missense_variant 0.11
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2859645 p.Gln258His missense_variant 0.94
pepQ 2860159 p.Ala87Gly missense_variant 0.12
ald 3086987 p.Gln56His missense_variant 0.97
fbiD 3339734 p.Ala206Gly missense_variant 0.25
Rv3083 3448497 c.-7T>A upstream_gene_variant 0.67
fprA 3474119 p.Met38Thr missense_variant 0.99
whiB7 3568428 c.252A>G synonymous_variant 0.4
whiB7 3568431 c.249C>G synonymous_variant 0.18
rpoA 3878597 c.-90G>C upstream_gene_variant 0.6
rpoA 3878630 c.-123G>C upstream_gene_variant 0.29
rpoA 3878637 c.-130G>C upstream_gene_variant 0.25
rpoA 3878641 c.-134C>G upstream_gene_variant 0.53
embC 4240409 p.Pro183Ala missense_variant 0.22
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243408 p.Thr59Asn missense_variant 0.97
embB 4246527 p.Ala5Gly missense_variant 0.28
ethA 4326012 p.Gly488Trp missense_variant 0.95
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448498 c.-5_*1408del transcript_ablation 1.0