TB-Profiler result

Run: SRR16156244

Summary

Run ID: SRR16156244

Sample name:

Date: 03-04-2023 16:34:05

Number of reads: 3823181

Percentage reads mapped: 99.77

Strain: lineage4.9.1

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
lineage4.9.1 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8978 c.1677C>T synonymous_variant 1.0
mshA 575389 c.42C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781609 p.Ser17Asn missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.24
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289138 p.Leu35Arg missense_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.28
fbiD 3339385 p.Asp90Asn missense_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.64
whiB7 3568428 c.252A>G synonymous_variant 0.21
rpoA 3878641 c.-134C>G upstream_gene_variant 0.41
whiB6 4338595 c.-75delG upstream_gene_variant 1.0