TB-Profiler result

Run: SRR16370694
Summary

Run ID: SRR16370694

Sample name:

Date: 03-04-2023 17:40:07

Number of reads: 2532562

Percentage reads mapped: 99.54

Strain: lineage4.1.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 1.0
lineage4.1.1 Euro-American (X-type) X1;X2;X3 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576751 p.Lys468Asn missense_variant 0.25
rpoB 760493 c.687C>A synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
rpoC 766070 c.2701C>T synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.12
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.11
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.11
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.11
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.11
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.11
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.11
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.11
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.12
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.13
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.13
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.14
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.18
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.22
rrs 1472504 n.659A>T non_coding_transcript_exon_variant 0.33
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.33
rrs 1472523 n.678A>G non_coding_transcript_exon_variant 0.29
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.29
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.29
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.29
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.29
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.29
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.25
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.2
rrs 1472612 n.767G>T non_coding_transcript_exon_variant 0.2
rrl 1474170 n.513G>T non_coding_transcript_exon_variant 0.17
rrl 1475698 n.2041G>T non_coding_transcript_exon_variant 0.25
inhA 1674616 p.Asn139Tyr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 0.99
ald 3086987 p.Gln56His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3641447 p.Thr302Met missense_variant 1.0
rpoA 3877553 p.Glu319Lys missense_variant 1.0
embC 4240897 c.1035C>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4249408 c.2895G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0