TB-Profiler result

Run: SRR16962453
Summary

Run ID: SRR16962453

Sample name:

Date: 03-04-2023 17:47:52

Number of reads: 929825

Percentage reads mapped: 99.73

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5472 p.Ala78Val missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 761736 p.Ile644Val missense_variant 0.11
rpoC 763348 c.-22C>T upstream_gene_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 778609 c.-129G>A upstream_gene_variant 0.11
mmpL5 778738 c.-258G>C upstream_gene_variant 0.13
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460992 c.-53A>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473810 n.153C>G non_coding_transcript_exon_variant 0.15
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475399 n.1742T>G non_coding_transcript_exon_variant 0.25
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169487 p.Asn376Asp missense_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ribD 2987308 p.Ala157Val missense_variant 0.11
fbiD 3339734 p.Ala206Gly missense_variant 0.3
fbiD 3339746 p.Ala210Gly missense_variant 0.33
fprA 3474418 p.Phe138Ile missense_variant 0.12
alr 3840764 c.657G>C synonymous_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.38
clpC1 4040282 c.423G>A synonymous_variant 1.0
embC 4241411 p.Ile517Val missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.56
embB 4248324 p.Ala604Gly missense_variant 0.24
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0